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SOST / Sclerostin

sclerostin

Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.

Gene Name: sclerostin
Synonyms: SOST, Sclerostin, Sclerosteosis, CDD, VBCH
Target Sequences: NM_025237 NP_079513.1 Q9BQB4

☰ Filters
Products
Proteins (11)
Over-Expression Lysate (2)
Recombinant (9)
SOST / Sclerostin (11)
No (11)
10His, N-terminus + Myc, C-terminus (1)
6His, C-terminus (4)
His (1)
His-GST (2)
Myc-DDK (Flag) (2)
Human (5)
Mouse (3)
Rat (2)
293T Cells (1)
CHO Cells (1)
E. coli (3)
HEK 293 Cells (1)
Human Cells (3)
Mammalian Cells (2)
Purified (3)
Low endotoxin level (5)
Biologically active (1)
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
21.9kD
10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353
SOST / Sclerostin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
21.5 kDa
20 µg/$150
SOST / Sclerostin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
21.5 kDa
100 µg/$494
Select
CHO Cells
None
Biologically active
21.5 kDa or 28-35 kDa
20 µg/$349; 5 µg/$268
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
23 kDa
20 µg/$525
SOST / Sclerostin Protein - Recombinant Sclerostin By SDS-PAGE
Select
E. coli
His-GST
51.4 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
SOST / Sclerostin Protein - Recombinant Sclerostin By SDS-PAGE
Select
E. coli
His-GST
50.7 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
SOST / Sclerostin Protein - Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of Recombinant Rat Sclerostin(Sost) could indicate that this peptide derived from E.coli-expressed Rattus norvegicus (Rat) Sost.
Select
E. coli
10His, N-terminus + Myc, C-terminus
28.0 kDa
1 mg/$1,679; 100 µg/$598; 20 µg/$405
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
21.9 kDa
10 µg/$317; 50 µg/$524
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
22.3kD
10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
22.3 kDa
10 µg/$317; 50 µg/$524
Viewing 1-11 of 11 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).