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SORD / Sorbitol Dehydrogenase

sorbitol dehydrogenase

Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.

Gene Name:	sorbitol dehydrogenase
Synonyms:	SORD, L-iditol 2-dehydrogenase, SORD1, Sorbitol dehydrogenase
Target Sequences:	NM_003104 NP_003095.2 Q00796

Sorbitol Dehydrogenase (SDH) Assay Kit (Colorimetric) - LS-K239

Type:

Detection/Quantition

Target:

SORD / Sorbitol Dehydrogenase

Application:

Spectrophotometry (visible)

Price:

100 Tests/$565

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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