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SORD / Sorbitol Dehydrogenase
sorbitol dehydrogenase
Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.
| Gene Name: | sorbitol dehydrogenase |
| Synonyms: | SORD, L-iditol 2-dehydrogenase, SORD1, Sorbitol dehydrogenase |
| Target Sequences: | NM_003104 NP_003095.2 Q00796 |
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SORD / Sorbitol Dehydrogenase
(102)
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(17)
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Detection/Quantition
SORD / Sorbitol Dehydrogenase
Spectrophotometry (visible)
100 Tests/$565
Sandwich
96-Well Microplate
Human
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$798
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (OTI17E7) Antibody
Human
Flo, IF
Unconjugated
100 µl/$434
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (Carrier-free) (OTI17E7) Antibody
Human
Flo, IF
Unconjugated, Carrier-free
100 µg/$511
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (OTI1D5) Antibody
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (Carrier-free) (OTI1D5) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (OTI9E7) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (Carrier-free) (OTI9E7) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (OTI15H2) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (Carrier-free) (OTI15H2) Antibody
Human
Flo, WB
Unconjugated, Carrier-free
100 µg/$511
SORD / Sorbitol Dehydrogenase Goat anti-Human Polyclonal (aa345-357) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
![SORD / Sorbitol Dehydrogenase Antibody - Immunoperoxidase of monoclonal antibody to SORD on formalin-fixed paraffin-embedded human kidney. [antibody concentration 1.2 ug/ml]](https://lsbio-7d62.kxcdn.com/image2/sord-sorbitol-dehydrogenase-antibody-clone-4d3-ls-c133945/53383_4974786.jpg)
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (4D3) Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$423
SORD / Sorbitol Dehydrogenase Rabbit anti-Human Polyclonal (aa72-121) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (AT10F4) Antibody
Human
ELISA, Flo, ICC, WB
Unconjugated
50 µl/$303; 100 µl/$365
SORD / Sorbitol Dehydrogenase Rabbit anti-Sheep Polyclonal Antibody
Sheep
ELISA, IF, IHC, WB
Unconjugated
1 mg/$520
SORD / Sorbitol Dehydrogenase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (OTI2A10) Antibody
IHC, IHC-P, WB
Unconjugated
100 µl/$434
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (OTI12A7) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (OTI9G9) Antibody
Human
Flo, IF
Unconjugated
100 µl/$434
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (Carrier-free) (OTI9G9) Antibody
Human
Flo, IF
Unconjugated, Carrier-free
100 µg/$511
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (OTI13G5) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
SORD / Sorbitol Dehydrogenase Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
SORD / Sorbitol Dehydrogenase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (OTI4E5) Antibody
Human
Flo, IF
Unconjugated
100 µl/$434
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