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SNX9 / WISP

sorting nexin 9

Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Promotes internalization of TNFR. Promotes degradation of EGFR after EGF signaling. Stimulates the GTPase activity of DNM1. Promotes DNM1 oligomerization. Promotes activation of the Arp2/3 complex by WASL, and thereby plays a role in the reorganization of the F-actin cytoskeleton. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Has lower affinity for membranes enriched in phosphatidylinositol 3-phosphate.

Gene Name: sorting nexin 9
Synonyms: SNX9, MST155, Protein SDP1, SH3PX1, SH3PXD3A, SDP1, Sorting nexin 9, WISP, MSTP155, Sorting nexin-9
Target Sequences: NM_016224 NP_057308.1 Q9Y5X1

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Products
Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
SNX9 / WISP (5)
No (5)
GST (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
SNX9 / WISP Protein - Recombinant  Sorting Nexin 9 By SDS-PAGE
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E. coli
His-T7
43.8 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
SNX9 / WISP Protein - Purified recombinant protein SNX9 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
66.4 kDa
20 µg/$1,107
SNX9 / WISP Protein - 12.5% SDS-PAGE of human SNX9 stained with Coomassie Blue
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Wheat Germ Extract
GST
91.19 kDa
10 µg/$479; 25 µg/$670
SNX9 / WISP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
66.4 kDa
100 µg/$494
SNX9 / WISP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
66.4 kDa
20 µg/$150
Viewing 1-5 of 5 product results


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Products: Proteins


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).