SNX27

sorting nexin family member 27

Involved in the retrograde transport from endosome to plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins. Following internalization, endocytosed transmembrane proteins are delivered to early endosomes and recycled to the plasma membrane instead of being degraded in lysosomes. SNX27 specifically binds and directs sorting of a subset of transmembrane proteins containing a PDZ-binding motif at the C-terminus: following interaction with target transmembrane proteins, associates with the retromer complex, preventing entry into the lysosomal pathway, and promotes retromer-tubule based plasma membrane recycling. SNX27 also binds with the WASH complex. Interacts with membranes containing phosphatidylinositol-3-phosphate (PtdIns(3P)). May participate in establishment of natural killer cell polarity. Recruits CYTIP to early endosomes.

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Products

Antibodies (26)

Proteins (4)

Type

Over-Expression Lysate (2)

Primary (26)

Recombinant (2)

Target

SNX27 (30)

Reactivity

Human (26)

Mouse (7)

Rat (8)

Bat (3)

Bovine (7)

Chicken (3)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Guinea pig (3)

Hamster (3)

Horse (3)

Monkey (3)

Orangutan (3)

Pig (3)

Rabbit (3)

Zebrafish (7)

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Application

IHC (12)

IHC-P (10)

WB (23)

ELISA (11)

ICC (10)

IF (10)

Host

rabbit (26)

Isotype

IgG (11)

Clonality

polyclonal pc (26)

Format

APC Conjugated (1)

Biotin Conjugated (5)

DY488 Conjugated (2)

DY550 Conjugated (2)

DY650 Conjugated (2)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (1)

Unconjugated (7)

Epitope

aa313-340 (7)

aa150-200 (5)

aa450-500 (5)

aa57-106 (4)

Publications

No (30)

Tag

GST (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

Select

SNX27 Antibody (aa450-500) LS-C143364

Antibody:

SNX27 Rabbit anti-Human Polyclonal (aa450-500) Antibody

Reactivity:

Zebrafish, Rat, Mouse, Bovine, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.1 ml/$386

Select

SNX27 Antibody (aa450-500, Biotin) LS-C143365

Antibody:

SNX27 Rabbit anti-Human Polyclonal (aa450-500) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

0.1 ml/$416

Select

SNX27 Antibody (aa450-500, DY550) LS-C143369

Antibody:

SNX27 Rabbit anti-Human Polyclonal (aa450-500) (DY550) Antibody

Reactivity:

Zebrafish, Rat, Bovine, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

DY550 Conjugated

Price:

0.1 ml/$416

Select

SNX27 Antibody (aa450-500, DY488) LS-C143367

Antibody:

SNX27 Rabbit anti-Human Polyclonal (aa450-500) (DY488) Antibody

Reactivity:

Zebrafish, Rat, Bovine, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

DY488 Conjugated

Price:

0.1 ml/$416

Select

SNX27 Antibody (aa450-500, DY650) LS-C143366

Antibody:

SNX27 Rabbit anti-Human Polyclonal (aa450-500) (DY650) Antibody

Reactivity:

Zebrafish, Rat, Bovine, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

DY650 Conjugated

Price:

0.1 ml/$416

• Unconjugated
• Biotin
• DY550
• DY488
• DY650

• Unconjugated
• Biotin
• DY550
• More...
  • DY488
  • DY650

Select

SNX27 Antibody (aa150-200) LS-C143358

Antibody:

SNX27 Rabbit anti-Human Polyclonal (aa150-200) Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.1 ml/$386

Select

SNX27 Antibody (aa150-200, Biotin) LS-C143359

Antibody:

SNX27 Rabbit anti-Human Polyclonal (aa150-200) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

0.1 ml/$416

Select

SNX27 Antibody (aa150-200, DY488) LS-C143361

Antibody:

SNX27 Rabbit anti-Human Polyclonal (aa150-200) (DY488) Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

DY488 Conjugated

Price:

0.1 ml/$416

Select

SNX27 Antibody (aa150-200, DY650) LS-C143360

Antibody:

SNX27 Rabbit anti-Human Polyclonal (aa150-200) (DY650) Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

DY650 Conjugated

Price:

0.1 ml/$416

Select

SNX27 Antibody (aa150-200, DY550) LS-C143363

Antibody:

SNX27 Rabbit anti-Human Polyclonal (aa150-200) (DY550) Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

DY550 Conjugated

Price:

0.1 ml/$416

• Unconjugated
• Biotin
• DY488
• DY650
• DY550

• Unconjugated
• Biotin
• DY488
• More...
  • DY650
  • DY550

Select

SNX27 Antibody LS-C501445

Antibody:

SNX27 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

SNX27 Antibody (HRP) LS-C501455

Antibody:

SNX27 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

SNX27 Antibody (Biotin) LS-C501443

Antibody:

SNX27 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

SNX27 Antibody (FITC) LS-C501459

Antibody:

SNX27 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

SNX27 Antibody LS-C754286

Antibody:

SNX27 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

SNX27 Antibody (aa313-340) LS-C325257

Antibody:

SNX27 Rabbit anti-Human Polyclonal (aa313-340) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

SNX27 Antibody (aa313-340, HRP) LS-C540609

Antibody:

SNX27 Rabbit anti-Human Polyclonal (aa313-340) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

200 µl/$952

Select

SNX27 Antibody (aa313-340, Biotin) LS-C520468

Antibody:

SNX27 Rabbit anti-Human Polyclonal (aa313-340) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

SNX27 Antibody (aa313-340, FITC) LS-C241080

Antibody:

SNX27 Rabbit anti-Human Polyclonal (aa313-340) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

SNX27 Antibody (aa313-340, APC) LS-C241079

Antibody:

SNX27 Rabbit anti-Human Polyclonal (aa313-340) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

SNX27 Antibody (aa313-340, PE) LS-C241081

Antibody:

SNX27 Rabbit anti-Human Polyclonal (aa313-340) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE

Select

SNX27 Antibody (aa57-106) LS-C186772

Antibody:

SNX27 Rabbit anti-Human Polyclonal (aa57-106) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

SNX27 Antibody (aa57-106, HRP) LS-C472928

Antibody:

SNX27 Rabbit anti-Human Polyclonal (aa57-106) (HRP) Antibody

Reactivity:

Chicken, Zebrafish, Rat, Hamster, Pig, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

SNX27 Antibody (aa57-106, FITC) LS-C473077

Antibody:

SNX27 Rabbit anti-Human Polyclonal (aa57-106) (FITC) Antibody

Reactivity:

Chicken, Zebrafish, Rat, Hamster, Pig, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• FITC

• Unconjugated
• HRP
• FITC

Select

SNX27 Antibody (aa313-340) LS-C161371

Antibody:

SNX27 Rabbit anti-Human Polyclonal (aa313-340) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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