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SNX1

sorting nexin 1

May be involved in several stages of intracellular trafficking. Plays a role in targeting ligand-activated EGFR to the lysosomes for degradation after endocytosis from the cell surface and release from the Golgi. Component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).

Gene Name: sorting nexin 1
Synonyms: SNX1, HsT17379, SNX1A, Sorting nexin 1, Sorting nexin 1A, Sorting nexin-1, VPS5
Target Sequences: NM_003099 NP_003090.2 Q13596

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Products
Proteins (12)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (5)
Recombinant (6)
SNX1 (12)
No (12)
6His, N-terminus (2)
GST (1)
GST, N-terminus (1)
His (1)
His, N-Terminal (1)
His-SUMO (1)
Myc-DDK (Flag) (5)
Human (10)
293T Cells (2)
E. coli (2)
HEK 293 Cells (6)
Wheat Germ Extract (2)
Purified (2)
SNX1 Protein
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E. coli
His
10 µg/$298; 50 µg/$417; 20 µg/$367; 100 µg/$564; 250 µg/$985; 500 µg/$1,480
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E. coli
His-SUMO
75.07 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
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HEK 293 Cells
6His, N-terminus
70-90 kDa
100 µg/$298
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HEK 293 Cells
6His, N-terminus
70-90 kDa
200 µl/$283
SNX1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SNX1 Protein
Select
HEK 293 Cells
His, N-Terminal
63 kDa (80 kDa reducing conditions)
10 µg/$289; 100 µg/$432; 50 µg/$360
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293T Cells
Myc-DDK (Flag)
58.9 kDa
20 µg/$150
SNX1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
51.6 kDa
20 µg/$215
SNX1 Protein - Purified recombinant protein SNX1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
58.9 kDa
20 µg/$1,107
SNX1 Protein - 12.5% SDS-PAGE of human SNX1 stained with Coomassie Blue
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Wheat Germ Extract
GST
85.5 kDa
10 µg/$479; 25 µg/$670
SNX1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
58.9 kDa
100 µg/$494
SNX1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
51.6 kDa
100 µg/$710
Viewing 1-12 of 12 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).