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SNTG2 / SYN5
syntrophin, gamma 2
SNTG2 / SYN5 is a protein belonging to the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a protein component of a mechanosensitive sodium channel that affects channel gating. Absence or reduction of this protein product has been associated with Duchenne muscular dystrophy. There is evidence of alternative splicing yet the full-length nature of these variants has not been described.
| Gene Name: | syntrophin, gamma 2 |
| Synonyms: | SNTG2, G2SYN, Gamma-2-syntrophin, Syntrophin-5, SYN5, Syntrophin, gamma 2 |
| Target Sequences: | NP_061841.2 Q9NY99 |
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