SNTA1 / Syntrophin Alpha 1

syntrophin, alpha 1

Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue.

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

SNTA1 / Syntrophin Alpha 1 (6)

Publications

No (6)

Tag

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

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SNTA1 / Syntrophin Alpha 1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99964

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.7 kDa

Price:

100 µg/$494

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Human SNTA1 / Syntrophin Alpha 1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68081

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.7 kDa

Price:

20 µg/$1,107

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Human SNTA1 / Syntrophin Alpha 1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81393

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.7 kDa

Price:

20 µg/$150

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Human SNTA1 / Syntrophin Alpha 1 Protein (Recombinant GST, N-terminus) (aa193-300) - LS-G60163

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human SNTA1 / Syntrophin Alpha 1 Protein (Recombinant His) - LS-G1583

Source:

E. coli

Tag:

His

Price:

50 µg/$373; 250 µg/$769; 10 µg/$276; 20 µg/$329; 100 µg/$479; 500 µg/$1,243

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Human SNTA1 / Syntrophin Alpha 1 Protein (Recombinant GST) (Full Length) - LS-G30488

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

80.3 kDa

Price:

10 µg/$479; 25 µg/$670

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