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The protein encoded by this gene is a homolog of the U1-snRNP binding protein. The N-terminal half contains a RNA recognition motif and the C-terminal half is rich in Arg/Asp and Arg/Glu dipeptides, which is a characteristic of a variety of splicing factors. This protein is a component of the U11/U12 small nuclear ribonucleoproteins (snRNP) that form part of the U12-type spliceosome. Alternative splicing results in multiple transcript variants encoding two distinct isoforms and representing a non-protein coding variant.
Gene Name: | small nuclear ribonucleoprotein 35kDa (U11/U12) |
Synonyms: | SNRNP35, HM-1, Protein HM-1, U11/U12-35K, U11/U12 snRNP 35 kDa protein, U11/U12 snRNP 35K, U1SNRNPBP, HM1 |
Target Sequences: | NM_007020 Q16560 Q16560 |
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