Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1.
Gene Name: | NUAK family, SNF1-like kinase, 2 |
Family/Subfamily: | Protein Kinase , CAMKL |
Synonyms: | NUAK2, OMPHK2, SNARK, Omphalocele kinase 2, SNF1/AMP kinase-related kinase, NUAK family SNF1-like kinase 2 |
Target Sequences: | BC017306 BAC11234.1 Q9H093 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.