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SNAP25

synaptosomal-associated protein, 25kDa

Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene.

Gene Name: synaptosomal-associated protein, 25kDa
Family/Subfamily: SNAP-25 , Not assigned-Other
Synonyms: SNAP25, BA416N4.2, DJ1068F16.2, SNAP, SUP, Super protein, RIC4, SEC9, SNAP-25, RIC-4
Target Sequences: NM_003081 NP_003072.2 P60880

Publications (3)

1
Isolation of a nanomolar scFv inhibiting the endopeptidase activity of botulinum toxin A, by single-round panning of an immune phage-displayed library of macaque origin. Chahboun S, Hust M, Liu Y, Pelat T, Miethe S, Helmsing S, Jones RG, Sesardic D, Thullier P. BMC biotechnology. 2011 11:113. (ELISA) [Full Text Article] [PubMed:22111995] [PMC:PMC3252318] Related Antibodies: LS-C39152.
2
Septin dynamics are essential for exocytosis. Tokhtaeva E, Capri J, Marcus EA, Whitelegge JP, Khuzakhmetova V, Bukharaeva E, Deiss-Yehiely N, Dada LA, Sachs G, Fernandez-Salas E, Vagin O. The Journal of biological chemistry. 2015 290:5280-97. (IHC; Human) [Full Text Article] [PubMed:25575596] [PMC:PMC4342448] Related Antibodies: LS-C549509.
3
Resident CAPS on dense-core vesicles docks and primes vesicles for fusion. Kabachinski G, Kielar-Grevstad DM, Zhang X, James DJ, Martin TF. Molecular biology of the cell. 2016 27:654-68. (ICC; Rat) [Full Text Article] [PubMed:26700319] [PMC:PMC4750925]

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ELISA Kits (18)
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SNAP25 (18)
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Mouse (6)
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Brain Tissue Homogenates (1)
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Tissue Homogenates (4)
SNAP25 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
SNAP25 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$587
SNAP25 ELISA Kit
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Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
SNAP25 ELISA Kit
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Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
SNAP25 ELISA Kit
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Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$669
SNAP25 ELISA Kit
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Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
SNAP25 ELISA Kit
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Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$669
SNAP25 ELISA Kit
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Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
SNAP25 ELISA Kit
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Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$783
SNAP25 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
SNAP25 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
SNAP25 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Brain Tissue Homogenates
1 Plate/$579
SNAP25 ELISA Kit
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Sandwich CLIA
96-Well Strip Plate
Rat
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
SNAP25 ELISA Kit
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Custom
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
1 Plate/$730
SNAP25 ELISA Kit
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Custom
96-Well Microplate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$748
SNAP25 ELISA Kit
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Custom
96-Well Microplate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
SNAP25 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit, Mouse, Bovine, Human, Rat, Pig
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$730
SNAP25 ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).