SNAI1 / SNAIL-1

snail family zinc finger 1

Involved in induction of the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. Binds to 3 E-boxes of the E-cadherin/CDH1 gene promoter and to the promoters of CLDN7 and KRT8 and, in association with histone demethylase KDM1A which it recruits to the promoters, causes a decrease in dimethylated H3K4 levels and represses transcription. Associates with EGR1 and SP1 to mediate tetradecanoyl phorbol acetate (TPA)-induced up-regulation of CDKN2B, possibly by binding to the CDKN2B promoter region 5'-TCACA-3. In addition, may also activate the CDKN2B promoter by itself.

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Products

ELISA Kits (3)

Type

Cell-Based (1)

Cell-Based Phosphorylation (1)

Sandwich (1)

Target

SNAI1 / SNAIL-1 (3)

Reactivity

Human (3)

Mouse (2)

Format

96-Well Microplate (2)

96-Well Strip Plate (1)

Publications

No (2)

Yes (1)

Sample Type

Adherent Cell Cultures (1)

Cell Lysates (1)

Plasma (1)

Serum (1)

Tissue Homogenates (1)

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Mouse/Human SNAI1 / SNAIL-1 (Cell-Based ELISA) ELISA Kit - LS-F2317

(4.0) Rating

(1) Publication(s)

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$534

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Human SNAI1 / SNAIL-1 (Sandwich ELISA) ELISA Kit - LS-F8875

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$730

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Mouse/Human Phospho-SNAI1 / SNAIL-1 (Ser246) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1439

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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