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SMYD2

SET and MYND domain containing 2

Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'.

Gene Name: SET and MYND domain containing 2
Synonyms: SMYD2, HSKM-B, KMT3C, Lysine N-methyltransferase 3C, ZMYND14
Target Sequences: NM_020197 NP_064582.2 Q9NRG4

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Products
Antibodies (27)
Primary (27)
SMYD2 (27)
Human (27)
Mouse (17)
Rat (9)
Bat (3)
Bovine (6)
Chimpanzee (3)
Dog (6)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (6)
Pig (6)
Rabbit (3)
Zebrafish (3)
IHC (2)
IHC-P (1)
WB (21)
ELISA (9)
IF (4)
IP (1)
Peptide-ELISA (2)
rabbit (24)
mouse (3)
IgG (15)
IgG2b (1)
monoclonal mc (3)
polyclonal pc (24)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
Unconjugated (18)
C-Terminus (4)
aa107-156 (4)
Internal (2)
Leu148 (1)
aa120-152 (1)
aa383-433 (1)
aa99-148 (1)
No (27)
SMYD2 Antibody - Western blot detection of KMT3C / SMYD2 in 3T3, HT1080, A431 and Jurkat cell lysates and using KMT3C / SMYD2 mouse monoclonal antibody (1:1000 dilution). Predicted band size: 50KDa. Observed band size: 50KDa.
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SMYD2 Mouse anti-Human Monoclonal Antibody
Mouse, Human
WB
Unconjugated
100 µl/$391
SMYD2 Antibody - Immunohistochemistry of paraffin-embedded human small intestine tissue at dilution of 1:100
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SMYD2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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SMYD2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
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SMYD2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
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SMYD2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
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SMYD2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
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SMYD2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
SMYD2 Antibody - Immunofluorescence analysis of HeLa cells.
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SMYD2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
20 µl/$275; 100 µl/$389
SMYD2 Antibody - Western blot detection of KMT3C / SMYD2 in 3T3, HT1080, A431 and Jurkat cell lysates and using KMT3C / SMYD2 mouse mAb (1:1000 diluted). Predicted band size: 50KDa. Observed band size: 50KDa.
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SMYD2 Mouse anti-Human Monoclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
SMYD2 Antibody - Western blot of SMYD2 antibody
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SMYD2 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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SMYD2 Rabbit anti-Human Polyclonal (aa383-433) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
SMYD2 Antibody - Western blot analysis of lysate from HT29 cells, using SMYD2 antibody.
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SMYD2 Rabbit anti-Human Polyclonal (aa99-148) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
SMYD2 Antibody - Western blot analysis SMYD2 using LOVO cells whole cells lysates
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SMYD2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SMYD2 Antibody - Western blot of SYMD2 (arrow) using rabbit polyclonal SYMD2 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SYMD2 gene (Lane 2) (Origene Technologies).
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SMYD2 Rabbit anti-Human Polyclonal (aa120-152) Antibody
Human
WB
Unconjugated
400 µl/$393
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SMYD2 Mouse anti-Human Monoclonal Antibody
Mouse, Human
WB
Unconjugated
50 µl/$356; 100 µl/$461
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SMYD2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$375; 200 µl/$473; 400 µl/$648
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SMYD2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
SMYD2 Antibody - Western blot analysis of SMYD2 expression in HEK293T (A); HeLa (B) whole cell lysates.
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SMYD2 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
SMYD2 Antibody - Western blot of SMYD2 (L148) pAb in extracts from HT29 cells.
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SMYD2 Rabbit anti-Human Polyclonal (Leu148) Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
SMYD2 Antibody - SMYD2 antibody Western blot of ACHN lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SMYD2 Rabbit anti-Human Polyclonal (aa107-156) Antibody
Human
WB
Unconjugated
100 µl/$424
SMYD2 Antibody - SMYD2 antibody Western blot of ACHN lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SMYD2 Rabbit anti-Human Polyclonal (aa107-156) (Biotin) Antibody
Mouse, Dog, Guinea pig, Bovine, Pig, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
SMYD2 Antibody - SMYD2 antibody Western blot of SH-SYSY lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SMYD2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
SMYD2 Antibody - SMYD2 antibody Western blot of SH-SYSY lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SMYD2 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Zebrafish, Pig, Horse, Bat, Rabbit, Mouse, Dog, Bovine, Rat, Human, Monkey, Gibbon
WB
HRP Conjugated
100 µl/$469
SMYD2 Antibody - SMYD2 antibody Western blot of SH-SYSY lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SMYD2 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Zebrafish, Pig, Horse, Bat, Rabbit, Mouse, Dog, Bovine, Rat, Human, Monkey, Gibbon
WB
Biotin Conjugated
100 µl/$469
SMYD2 Antibody - SMYD2 antibody Western blot of SH-SYSY lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SMYD2 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Zebrafish, Pig, Horse, Bat, Rabbit, Mouse, Dog, Bovine, Rat, Human, Monkey, Gibbon
WB
FITC Conjugated
100 µl/$469
Viewing 1-25 of 27 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).