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SMPD2
sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
Converts sphingomyelin to ceramide. Hydrolyze 1-acyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PC) and 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-platelet-activating factor). The physiological substrate seems to be Lyso-PAF.
| Gene Name: | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| Synonyms: | SMPD2, ISC1, NSMASE1, Sphingomyelinase neutral, N-SMase, NSMASE, Lyso-PAF-PLC, Neutral sphingomyelinase |
| Target Sequences: | AJ222801 CAA10995.1 O60906 |
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Proteins
(5)
Type
Over-Expression Lysate
(2)
Recombinant
(3)
Target
SMPD2
(5)
Publications
No
(5)
Tag
GST
(1)
His-GST
(1)
His-GST, N-terminus
(1)
Myc-DDK (Flag)
(2)
Species
Human
(3)
Rat
(1)
Source
293T Cells
(1)
E. coli
(2)
HEK 293 Cells
(1)
Wheat Germ Extract
(1)
Purification
Purified
(2)
Wheat Germ Extract
GST
72.27 kDa
10 µg/$479; 25 µg/$670
E. coli
His-GST
59.2 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
293T Cells
Myc-DDK (Flag)
47.5 kDa
20 µg/$150
HEK 293 Cells
Myc-DDK (Flag)
47.5 kDa
100 µg/$494
E. coli
His-GST, N-terminus
66.9kDa
10 µg/$279; 50 µg/$425; 200 µg/$850; 100 µg/$680; 1 mg/$1,944; 500 µg/$1,490; 5 mg/$2,969; 2 mg/$2,131
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