Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Location
Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
SMPD1 / Acid Sphingomyelinase
sphingomyelin phosphodiesterase 1, acid lysosomal
Converts sphingomyelin to ceramide. Also has phospholipase C activities toward 1,2-diacylglycerolphosphocholine and 1,2-diacylglycerolphosphoglycerol. Isoform 2 and isoform 3 have lost catalytic activity.
| Gene Name: | sphingomyelin phosphodiesterase 1, acid lysosomal |
| Family/Subfamily: | Phosphodiesterase - Other , not assigned-Phosphodiesterase - Other |
| Synonyms: | SMPD1, Acid sphingomyelinase, ASM, NPD, ASMASE |
| Target Sequences: | NM_000543 NP_000534.3 P17405 |
Publications (3)
1
Regulation of the amount of ceramide-1-phosphate synthesized in differentiated human podocytes. Shamroop Kumar Mallela, Alla Mitrofanova, Sandra Merscher, Alessia Fornoni. Biochimica et biophysica acta. Molecular and cell biology of lipids. 2019 December;1864:158517. [Full Text Article]
[PubMed:31487557]
[PMC:PMC6832884]
Related Antibodies: LS-C334919.
2
Penfluridol targets acid sphingomyelinase to inhibit TNF signaling and is therapeutic against inflammatory autoimmune diseases. Yue-Hong Chen, Rong-Han Liu, Ya-Zhou Cui, Aubryanna Hettinghouse, Wen-Yu Fu, Lei Zhang, Chen Zhang, Chuan-Ju Liu. Arthritis research & therapy. 2022 January;24:27. [Full Text Article]
[PubMed:35045889]
[PMC:PMC8767691]
Related Antibodies: LS-C334919.
3
Endothelial Acid Sphingomyelinase Promotes NLRP3 Inflammasome and Neointima Formation During Hypercholesterolemia. Xinxu Yuan, Owais M Bhat, Yao Zou, Xiang Li, Yang Zhang, Pin-Lan Li. Journal of lipid research. 2022 October;63:100298. [Full Text Article]
[PubMed:36252682]
[PMC:PMC9672920]
Related Antibodies: LS-C334919.
☰ Filters
Products
Proteins
(10)
Type
Over-Expression Lysate
(4)
Recombinant
(6)
Target
SMPD1 / Acid Sphingomyelinase
(10)
Publications
No
(10)
Tag
GST
(1)
GST, N-terminus
(1)
His
(2)
His-T7
(1)
Myc-DDK (Flag)
(5)
Species
Human
(7)
Mouse
(1)
Source
293T Cells
(2)
Baculovirus
(2)
E. coli
(1)
HEK 293 Cells
(3)
Wheat Germ Extract
(2)
Purification
Purified
(2)
Low Endotoxin Level
Low endotoxin level
(2)
E. coli
His-T7
33.9 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
Wheat Germ Extract
GST
65.78 kDa
2 µg/$439
293T Cells
Myc-DDK (Flag)
69.94 kDa
20 µg/$215
293T Cells
Myc-DDK (Flag)
69.81 kDa
20 µg/$215
Wheat Germ Extract
GST, N-terminus
2 µg/$439
Baculovirus
His
Less than 1.0 EU/µg protein (determined by LAL method).
66.3 kDa
50 µg/$1,070
HEK 293 Cells
Myc-DDK (Flag)
69.94 kDa
100 µg/$710
Baculovirus
His
Less than 1.0 EU/µg protein (determined by LAL method).
66.3 kDa
50 µg/$854
HEK 293 Cells
Myc-DDK (Flag)
65 kDa
20 µg/$1,107
HEK 293 Cells
Myc-DDK (Flag)
69.81 kDa
100 µg/$710
Viewing 1-10
of 10
product results
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
