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SMPD1 / Acid Sphingomyelinase

sphingomyelin phosphodiesterase 1, acid lysosomal

Converts sphingomyelin to ceramide. Also has phospholipase C activities toward 1,2-diacylglycerolphosphocholine and 1,2-diacylglycerolphosphoglycerol. Isoform 2 and isoform 3 have lost catalytic activity.

Gene Name: sphingomyelin phosphodiesterase 1, acid lysosomal
Family/Subfamily: Phosphodiesterase - Other , not assigned-Phosphodiesterase - Other
Synonyms: SMPD1, Acid sphingomyelinase, ASM, NPD, ASMASE
Target Sequences: NM_000543 NP_000534.3 P17405

Publications (3)

1
Regulation of the amount of ceramide-1-phosphate synthesized in differentiated human podocytes. Shamroop Kumar Mallela, Alla Mitrofanova, Sandra Merscher, Alessia Fornoni. Biochimica et biophysica acta. Molecular and cell biology of lipids. 2019 December;1864:158517. [Full Text Article] [PubMed:31487557] [PMC:PMC6832884] Related Antibodies: LS-C334919.
2
Penfluridol targets acid sphingomyelinase to inhibit TNF signaling and is therapeutic against inflammatory autoimmune diseases. Yue-Hong Chen, Rong-Han Liu, Ya-Zhou Cui, Aubryanna Hettinghouse, Wen-Yu Fu, Lei Zhang, Chen Zhang, Chuan-Ju Liu. Arthritis research & therapy. 2022 January;24:27. [Full Text Article] [PubMed:35045889] [PMC:PMC8767691] Related Antibodies: LS-C334919.
3
Endothelial Acid Sphingomyelinase Promotes NLRP3 Inflammasome and Neointima Formation During Hypercholesterolemia. Xinxu Yuan, Owais M Bhat, Yao Zou, Xiang Li, Yang Zhang, Pin-Lan Li. Journal of lipid research. 2022 October;63:100298. [Full Text Article] [PubMed:36252682] [PMC:PMC9672920] Related Antibodies: LS-C334919.

☰ Filters
Products
ELISA Kits (22)
Competitive EIA (1)
Custom (1)
Sandwich (19)
Sandwich CLIA (1)
SMPD1 / Acid Sphingomyelinase (22)
Human (9)
Mouse (1)
Rat (1)
Chicken (2)
Monkey (2)
Porcine (2)
Rabbit (2)
Sheep (2)
12 x 8-Well Microstrips (1)
96-Well Microplate (2)
96-Well Strip Plate (18)
No (22)
Cell Culture Supernatants (3)
Cerebrospinal Fluid (1)
Heparin Plasma (1)
Plasma (10)
Serum (11)
Tissue Homogenates (2)
Urine (1)
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Sandwich
96-Well Microplate
Human
1.22 - 300 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$610
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Sandwich
96-Well Strip Plate
Human
1.25 - 80 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cerebrospinal Fluid, Plasma, Serum, Urine
1 Plate/$1,041
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
78.125 - 5000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Sandwich
96-Well Strip Plate
Porcine
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Sandwich
96-Well Strip Plate
Sheep
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$691
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
7.813 - 500 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
SMPD1 / Acid Sphingomyelinase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
SMPD1 / Acid Sphingomyelinase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
SMPD1 / Acid Sphingomyelinase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Sheep
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$691
SMPD1 / Acid Sphingomyelinase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
7.813 - 500 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
SMPD1 / Acid Sphingomyelinase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Sandwich
Human
15.6 - 1000 pg/ml
Cell Culture Supernatants, Heparin Plasma, Serum
1 Plate/$699
SMPD1 / Acid Sphingomyelinase ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
SMPD1 / Acid Sphingomyelinase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$798
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Competitive EIA
96-Well Strip Plate
Human
1 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
Viewing 1-22 of 22 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).