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Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Gene Name: | structural maintenance of chromosomes 4 |
Synonyms: | SMC4, HCAP-C, SMC protein 4, SMC4L1, SMC-4, XCAP-C homolog, CAP-C, CAPC |
Target Sequences: | NM_005496 NP_005487.3 Q9NTJ3 |
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