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Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Gene Name: | structural maintenance of chromosomes 2 |
Synonyms: | SMC2, HCAP-E, SMC protein 2, XCAP-E homolog, CAP-E, CAPE, SMC-2, SMC2L1 |
Target Sequences: | NM_006444 NP_006435.2 O95347 |
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