SMAD6

SMAD family member 6

Acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes. May block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding. Binds to regulatory elements in target promoter regions.

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Products

Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

SMAD6 (8)

Publications

No (8)

Tag

GST (1)

GST, N-terminus (1)

His-T7 (3)

Myc-DDK (Flag) (3)

Species

Human (5)

Mouse (1)

Rat (1)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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Mouse SMAD6 Protein (Recombinant His-T7) (aa116-364) - LS-G14775

Source:

E. coli

Tag:

His-T7

Molecular Weight:

30.8 kDa

Price:

10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164

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SMAD6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G126126

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.1 kDa

Price:

100 µg/$494

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Human SMAD6 Protein (Recombinant GST) (Full Length) - LS-G29243

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

80.96 kDa

Price:

2 µg/$439

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Human SMAD6 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66981

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.1 kDa

Price:

20 µg/$1,107

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Human SMAD6 Protein (Recombinant GST, N-terminus) (aa285-384) - LS-G59164

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human SMAD6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78850

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.1 kDa

Price:

20 µg/$150

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Human SMAD6 Protein (Recombinant His-T7) (aa261-495) - LS-G14776

Source:

E. coli

Tag:

His-T7

Molecular Weight:

29.7 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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Rat SMAD6 Protein (Recombinant His-T7) (aa171-441) - LS-G14778

Source:

E. coli

Tag:

His-T7

Molecular Weight:

33.3 kDa

Price:

10 µg/$287; 50 µg/$477; 100 µg/$762; 200 µg/$952; 1 mg/$2,083; 500 µg/$1,613; 5 mg/$3,333; 2 mg/$2,272

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