SMAD6

SMAD family member 6

Acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes. May block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding. Binds to regulatory elements in target promoter regions.

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Products

Antibodies (73)

Proteins (8)

ELISA Kits (4)

Type

Custom (3)

Over-Expression Lysate (2)

Primary (73)

Recombinant (6)

Sandwich (1)

Target

SMAD6 (85)

Reactivity

Human (53)

Mouse (30)

Rat (19)

Bovine (9)

Chicken (1)

Chimpanzee (12)

Dog (6)

Gibbon (12)

Guinea pig (3)

Horse (3)

Monkey (7)

Pig (10)

Rabbit (3)

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Application

IHC (17)

IHC-P (11)

WB (71)

Flo (7)

ELISA (20)

ICC (1)

IF (1)

Peptide-ELISA (2)

Host

rabbit (66)

mouse (7)

Product Group

IHCPlus (6)

Isotype

IgG (25)

IgG1 (3)

IgG2a,k (1)

IgG2b,k (3)

Clonality

monoclonal mc (7)

polyclonal pc (66)

Clone

1G2 (1)

2A6 (1)

4C8 (1)

4F3 (1)

5H3 (2)

Format

96-Well Strip Plate (4)

APC (3)

APC Conjugated (5)

Azide-free (2)

Biotin Conjugated (9)

Cy3 Conjugated (3)

Cy7 Conjugated (3)

FITC Conjugated (9)

HRP Conjugated (9)

PE Conjugated (5)

Unconjugated (30)

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Epitope

aa116-364 (8)

aa171-441 (8)

aa261-495 (8)

aa357-386 (7)

aa358-386 (7)

aa11-60 (4)

aa136-185 (4)

aa137-182 (4)

aa398-447 (4)

Internal (2)

C-Terminus (1)

aa323-372 (1)

aa85-99 (1)

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Publications

No (85)

Sample Type

Plasma (1)

Serum (1)

Tag

GST (1)

GST, N-terminus (1)

His-T7 (3)

Myc-DDK (Flag) (3)

Species

Human (5)

Mouse (1)

Rat (1)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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IHC-plus™ SMAD6 Antibody (clone 4F3) LS-B4368

(4.0) Rating

Antibody:

SMAD6 Mouse anti-Human Monoclonal (4F3) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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IHC-plus™ SMAD6 Antibody (aa323-372) LS-B12570

(4.0) Rating

Antibody:

SMAD6 Rabbit anti-Human Polyclonal (aa323-372) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$460

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IHC-plus™ SMAD6 Antibody (clone 1G2) LS-B4370

(4.0) Rating

Antibody:

SMAD6 Mouse anti-Human Monoclonal (1G2) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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IHC-plus™ SMAD6 Antibody (clone 4C8) LS-B4367

(4.0) Rating

Antibody:

SMAD6 Mouse anti-Human Monoclonal (4C8) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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IHC-plus™ SMAD6 Antibody (aa85-99) LS-B2065

(4.0) Rating

Antibody:

SMAD6 Rabbit anti-Human Polyclonal (aa85-99) Antibody

Reactivity:

Pig, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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SMAD6 Antibody (aa137-182) LS-C31183

Antibody:

SMAD6 Rabbit anti-Human Polyclonal (aa137-182) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$397

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SMAD6 Antibody (aa137-182, HRP) LS-C428375

Antibody:

SMAD6 Rabbit anti-Human Polyclonal (aa137-182) (HRP) Antibody

Reactivity:

Mouse, Dog, Bovine, Rat, Pig, Gibbon, Chimpanzee, Human

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$442

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SMAD6 Antibody (aa137-182, Biotin) LS-C428374

Antibody:

SMAD6 Rabbit anti-Human Polyclonal (aa137-182) (Biotin) Antibody

Reactivity:

Mouse, Dog, Bovine, Rat, Pig, Gibbon, Chimpanzee, Human

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$442

Select

SMAD6 Antibody (aa137-182, FITC) LS-C428376

Antibody:

SMAD6 Rabbit anti-Human Polyclonal (aa137-182) (FITC) Antibody

Reactivity:

Mouse, Dog, Bovine, Rat, Pig, Gibbon, Chimpanzee, Human

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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IHC-plus™ SMAD6 Antibody (clone 2A6) LS-B4369

(4.0) Rating

Antibody:

SMAD6 Mouse anti-Human Monoclonal (2A6) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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SMAD6 Antibody LS-C89113

Antibody:

SMAD6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$649

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Mouse SMAD6 Protein (Recombinant His-T7) (aa116-364) - LS-G14775

Source:

E. coli

Tag:

His-T7

Molecular Weight:

30.8 kDa

Price:

10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164

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SMAD6 Antibody (Internal) LS-C386097

Antibody:

SMAD6 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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SMAD6 Antibody (aa358-386) LS-C325194

Antibody:

SMAD6 Rabbit anti-Human Polyclonal (aa358-386) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

Unconjugated

Price:

200 µl/$734

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SMAD6 Antibody (aa358-386, Biotin) LS-C269640

Antibody:

SMAD6 Rabbit anti-Human Polyclonal (aa358-386) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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SMAD6 Antibody (aa358-386, FITC) LS-C269641

Antibody:

SMAD6 Rabbit anti-Human Polyclonal (aa358-386) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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SMAD6 Antibody (aa358-386, APC) LS-C269639

Antibody:

SMAD6 Rabbit anti-Human Polyclonal (aa358-386) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

SMAD6 Antibody (aa358-386, Azide-free, HRP) LS-C269642

Antibody:

SMAD6 Rabbit anti-Human Polyclonal (aa358-386) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

SMAD6 Antibody (aa358-386, PE) LS-C269645

Antibody:

SMAD6 Rabbit anti-Human Polyclonal (aa358-386) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

SMAD6 Antibody LS-C817311

Antibody:

SMAD6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF

Format:

Unconjugated

Price:

100 µl/$412

Select

SMAD6 Antibody LS-C808571

Antibody:

SMAD6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

SMAD6 Antibody (Internal) LS-C352482

Antibody:

SMAD6 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

30 µl/$255; 50 µl/$271; 100 µl/$299; 200 µl/$351

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SMAD6 Antibody LS-C416981

Antibody:

SMAD6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

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SMAD6 Antibody (C-Terminus) LS-C144963

Antibody:

SMAD6 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$440; 200 µl/$468

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SMAD6 Antibody LS-C749731

Antibody:

SMAD6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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