SMAD1

SMAD family member 1

SMAD1 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.

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Products

Proteins (12)

Type

Over-Expression Lysate (4)

Recombinant (8)

Target

SMAD1 (12)

Publications

No (12)

Tag

GST (1)

GST, N-terminus (3)

His (1)

His-T7 (2)

Myc-DDK (Flag) (5)

Species

Bovine (1)

Human (7)

Mouse (1)

Rat (1)

Source

293T Cells (2)

E. coli (4)

HEK 293 Cells (3)

Wheat Germ Extract (3)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (1)

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Human SMAD1 Protein (Recombinant GST) (Full Length) - LS-G29239

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

76.89 kDa

Price:

10 µg/$479; 25 µg/$670

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SMAD1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115659

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.1 kDa

Price:

100 µg/$494

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SMAD1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G122585

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.1 kDa

Price:

100 µg/$494

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Human SMAD1 Protein (Recombinant GST, N-terminus) (Met1-Ser465) - LS-G140398

Source:

E. coli

Tag:

GST, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

78.7 kDa

Price:

10 µg/$317; 50 µg/$524

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Bovine SMAD1 Protein (Recombinant His-T7) (aa270-465) - LS-G12559

Source:

E. coli

Tag:

His-T7

Molecular Weight:

26.0 kDa

Price:

10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334

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Mouse SMAD1 Protein (Recombinant His-T7) (aa271-465) - LS-G12562

Source:

E. coli

Tag:

His-T7

Molecular Weight:

25.6 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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Rat SMAD1 Protein (Recombinant His) (aa273-468) - LS-G12563

Source:

E. coli

Tag:

His

Molecular Weight:

23.8 kDa

Price:

10 µg/$294; 50 µg/$522; 100 µg/$832; 200 µg/$1,034; 1 mg/$2,192; 500 µg/$1,712; 5 mg/$3,641; 2 mg/$2,383

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Human SMAD1 Protein (Recombinant GST, N-terminus) (aa1-110) - LS-G59157

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human SMAD1 Protein (Recombinant GST, N-terminus) (aa176-259) - LS-G59161

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human SMAD1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68203

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.1 kDa

Price:

20 µg/$1,107

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Human SMAD1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81645

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.1 kDa

Price:

20 µg/$150

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Human SMAD1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81647

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.1 kDa

Price:

20 µg/$150

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