SLIT2

slit homolog 2 (Drosophila)

Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once they reached the floor plate by modulating the response to netrin. In vitro, silences the attractive effect of NTN1 but not its growth-stimulatory effect and silencing requires the formation of a ROBO1-DCC complex. May be implicated in spinal chord midline post-crossing axon repulsion. In vitro, only commissural axons that crossed the midline responded to SLIT2. In the developing visual system appears to function as repellent for retinal ganglion axons by providing a repulsion that directs these axons along their appropriate paths prior to, and after passage through, the optic chiasm. In vitro, collapses and repels retinal ganglion cell growth cones. Seems to play a role in branching and arborization of CNS sensory axons, and in neuronal cell migration. In vitro, Slit homolog 2 protein N-product, but not Slit homolog 2 protein C-product, repels olfactory bulb (OB) but not dorsal root ganglia (DRG) axons, induces OB growth cones collapse and induces branching of DRG axons. Seems to be involved in regulating leukocyte migration.

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Antibodies (49)

ELISA Kits (25)

Proteins (9)

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Competitive EIA (2)

Custom (2)

Over-Expression Lysate (2)

Primary (49)

Recombinant (7)

Sandwich (19)

Sandwich CLIA (2)

Target

SLIT2 (83)

Reactivity

Human (31)

Mouse (27)

Rat (15)

Bovine (1)

Chicken (2)

Guinea pig (1)

Hamster (1)

Horse (1)

Monkey (2)

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IHC-P (4)

WB (48)

ELISA (5)

Peptide-ELISA (2)

Host

rabbit (47)

mouse (1)

goat (1)

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IHCPlus (2)

Isotype

IgG (6)

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polyclonal pc (49)

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12 x 8-Well Microstrips (2)

96-Well Microplate (5)

96-Well Strip Plate (18)

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Epitope

aa1160-1333 (8)

aa1408-1519 (8)

aa1416-1528 (8)

aa209-374 (8)

aa31-197 (8)

aa1078-1090 (1)

aa209-370 (1)

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Yes (1)

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Cell Culture Supernatants (2)

Cell Lysates (2)

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Plasma (16)

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His (2)

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Myc-DDK (Flag) (3)

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Mouse (2)

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Source

293T Cells (1)

E. coli (5)

HEK 293 Cells (3)

Purification

Purified (3)

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Low endotoxin level (1)

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SLIT2 Antibody LS-C19086

(4.0) Rating

(1) Publication(s)

Antibody:

SLIT2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Chicken, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$567

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SLIT2 Antibody (aa1078-1090) LS-C55479

Antibody:

SLIT2 Goat anti-Human Polyclonal (aa1078-1090) Antibody

Reactivity:

Mouse, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey

Applications:

IHC-P, Peptide-ELISA

Format:

Unconjugated

Price:

100 µg/$503

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Human SLIT2 (Sandwich ELISA) ELISA Kit - LS-F21017

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.16 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Human SLIT2 (Sandwich ELISA) ELISA Kit - LS-F12612

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Human SLIT2 (Sandwich ELISA) ELISA Kit - LS-F4840

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$764

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Mouse SLIT2 (Sandwich ELISA) ELISA Kit - LS-F4841

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$782

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SLIT2 Antibody (aa31-197) LS-C296464

Antibody:

SLIT2 Rabbit anti-Mouse Polyclonal (aa31-197) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161

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SLIT2 Antibody (aa31-197, Biotin) LS-C300984

Antibody:

SLIT2 Rabbit anti-Mouse Polyclonal (aa31-197) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$311; 200 µl/$353; 500 µl/$496; 1 ml/$567; 2 ml/$769; 5 ml/$1,248

• Unconjugated
• Biotin

• Unconjugated
• Biotin

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Mouse SLIT2 (Sandwich ELISA) ELISA Kit - LS-F57327

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

156 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, EDTA Plasma, Heparin Plasma, Serum

Price:

1 Plate/$699

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Human SLIT2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71137

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

169.7 kDa

Price:

20 µg/$1,107

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SLIT2 Antibody (aa1416-1528) LS-B13918

Antibody:

SLIT2 Rabbit anti-Human Polyclonal (aa1416-1528) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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Rat SLIT2 (Sandwich ELISA) ELISA Kit - LS-F6346

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$715

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SLIT2 Antibody LS-C126299

Antibody:

SLIT2 Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$628

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SLIT2 Antibody (aa1416-1528, Biotin) LS-C297224

Antibody:

SLIT2 Rabbit anti-Human Polyclonal (aa1416-1528) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$308; 200 µl/$350; 500 µl/$489; 1 ml/$558; 2 ml/$749; 5 ml/$1,217

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SLIT2 Antibody (aa1160-1333, Biotin) LS-C300983

Antibody:

SLIT2 Rabbit anti-Human Polyclonal (aa1160-1333) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$308; 200 µl/$350; 500 µl/$489; 1 ml/$558; 2 ml/$749; 5 ml/$1,217

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SLIT2 Antibody (aa1160-1333) LS-B14605

Antibody:

SLIT2 Rabbit anti-Human Polyclonal (aa1160-1333) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

Human SLIT2 Protein (Recombinant His, N-Terminal) (Val1160-Cys1333) - LS-G12589

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

20.1 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Human SLIT2 Protein (Recombinant His, N-Terminal) (aa1416-1528) - LS-G12590

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

14.0 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Human SLIT2 (Sandwich ELISA) ELISA Kit - LS-F34060

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

SLIT2 Antibody LS-C403581

Antibody:

SLIT2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

SLIT2 Antibody LS-C751712

Antibody:

SLIT2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

SLIT2 Antibody LS-C778492

Antibody:

SLIT2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$357

Select

SLIT2 Antibody LS-C809768

Antibody:

SLIT2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

SLIT2 Antibody (aa1408-1519) LS-C372568

Antibody:

SLIT2 Rabbit anti-Mouse Polyclonal (aa1408-1519) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161

Select

SLIT2 Antibody LS-C750323

Antibody:

SLIT2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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