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SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
Functions as permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine); the affinity for its substrates differs between isoforms created by alternative splicing. Isoform 1 functions as permease that mediates the transport of the cationic amino acids (arginine, lysine and ornithine), and it has much higher affinity for arginine than isoform 2. Isoform 2 functions as low-affinity, high capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) (PubMed:9174363). May play a role in classical or alternative activation of macrophages via its role in arginine transport.
| Gene Name: | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| Family/Subfamily: | Transporter , Cationic amino acid transporter |
| Synonyms: | SLC7A2, ATRC2, CAT2, HCAT2, CAT-2 |
| Target Sequences: | NM_003046 NP_001008539.3 P52569 |
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