Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
SLC6A4 / SERT is an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.
Gene Name: | solute carrier family 6 (neurotransmitter transporter), member 4 |
Family/Subfamily: | Transporter , Neurotransmitter:sodium symporter |
Synonyms: | SLC6A4, 5HTT, 5HT transporter, 5-HTT, 5-HTTLPR, OCD1, SERT, Serotonin transporter, HSERT, SERT1 |
Target Sequences: | NM_001045 NP_001036.1 P31645 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.