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SLC6A4 / SERT

solute carrier family 6 (neurotransmitter transporter), member 4

SLC6A4 / SERT is an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.

Gene Name: solute carrier family 6 (neurotransmitter transporter), member 4
Family/Subfamily: Transporter , Neurotransmitter:sodium symporter
Synonyms: SLC6A4, 5HTT, 5HT transporter, 5-HTT, 5-HTTLPR, OCD1, SERT, Serotonin transporter, HSERT, SERT1
Target Sequences: NM_001045 NP_001036.1 P31645

Publications (1)

1
Pathway of Maternal Serotonin to the Human Embryo and Fetus. Kliman HJ, Quaratella SB, Setaro AC, Siegman EC, Subha ZT, Tal R, Milano KM, Steck TL. Endocrinology. 2018 April;159:1609-1629. [Full Text Article] [PubMed:29381782] Related Antibodies: LS-C179236.

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Products
ELISA Kits (20)
Competitive EIA (1)
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Development Kit (1)
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SLC6A4 / SERT (20)
Human (7)
Mouse (4)
Rat (5)
Monkey (1)
Porcine (1)
Rabbit (1)
Product Group
DevKit DuoPlus (1)
12 x 8-Well Microstrips (1)
96-Well Microplate (1)
96-Well Strip Plate (17)
Antibody Pair and Standard (1)
No (20)
Cell Lysates (4)
Plasma (10)
Serum (10)
Tissue Homogenates (7)
SLC6A4 / SERT ELISA Kit
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Sandwich
96-Well Microplate
Human
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
SLC6A4 / SERT ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$748
SLC6A4 / SERT ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$783
SLC6A4 / SERT ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$730
SLC6A4 / SERT ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
SLC6A4 / SERT ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
SLC6A4 / SERT ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$669
SLC6A4 / SERT ELISA Kit
Select
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$669
SLC6A4 / SERT ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
1.563 - 100 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
SLC6A4 / SERT ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
SLC6A4 / SERT ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
SLC6A4 / SERT ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
7.813 - 500 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
SLC6A4 / SERT ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
SLC6A4 / SERT ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
SLC6A4 / SERT ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
SLC6A4 / SERT ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
SLC6A4 / SERT ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
500 Wells/$1,276; 1000 Wells/$1,903
SLC6A4 / SERT ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
SLC6A4 / SERT ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
1 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
SLC6A4 / SERT ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).