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SLC5A7 / Choline Transporter
solute carrier family 5 (sodium/choline cotransporter), member 7
Choline is a direct precursor of acetylcholine (ACh), a neurotransmitter of the central and peripheral nervous system that regulates a variety of autonomic, cognitive, and motor functions. SLC5A7 is a Na(+)- and Cl(-)- dependent high-affinity transporter that mediates the uptake of choline for acetylcholine synthesis in cholinergic neurons (Apparsundaram et al., 2000 [PubMed 11027560]).
| Gene Name: | solute carrier family 5 (sodium/choline cotransporter), member 7 |
| Family/Subfamily: | Transporter , Solute:sodium symporter |
| Synonyms: | SLC5A7, CHT, CHT1, Choline transporter, HCHT |
| Target Sequences: | NM_021815 NP_068587.1 Q9GZV3 |
Publications (2)
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