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SLC5A10 / SGLT5 is a member of the sodium/glucose transporter family. Members of this family are sodium-dependent transporters and can be divided into two subfamilies based on sequence homology, one that co-transports sugars and the second that transports molecules such as ascorbate, choline, iodide, lipoate, monocaroboxylates, and pantothenate. The protein encoded by this gene has the highest affinity for mannose and has been reported to be most highly expressed in the kidney. This protein may function as a kidney-specific, sodium-dependent mannose and fructose co-transporter. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Gene Name: | solute carrier family 5 (sodium/sugar cotransporter), member 10 |
Family/Subfamily: | Transporter , Solute:sodium symporter |
Synonyms: | SLC5A10, SGLT-5, Sodium/glucose cotransporter 5, Na(+)/glucose cotransporter 5, SGLT5, RK-D |
Target Sequences: | NM_152351 NP_689564.3 A0PJK1 |
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