SLC3A2 / CD98 Heavy Chain

solute carrier family 3 (amino acid transporter heavy chain), member 2

Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Required for normal and neoplastic cell growth. When associated with SLC7A5/LAT1, is also involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. When associated with SLC7A5 or SLC7A8, involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarized intestinal cells, by generating and delivering intracellular signals. When associated with SLC7A5, plays an important role in transporting L-leucine from the circulating blood to the retina across the inner blood-retinal barrier.

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Products

Antibodies (62)

Proteins (20)

ELISA Kits (5)

Type

Custom (1)

Over-Expression Lysate (7)

Primary (62)

Recombinant (13)

Sandwich (4)

Target

SLC3A2 / CD98 Heavy Chain (87)

Reactivity

Human (46)

Mouse (15)

Rat (11)

Pig (8)

Application

IHC (17)

IHC-Fr (2)

IHC-P (5)

WB (49)

Flo (11)

ELISA (11)

Func (1)

IF (2)

IP (2)

Peptide-ELISA (1)

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Host

rabbit (51)

mouse (11)

Product Group

IHCPlus (2)

Isotype

IgG (14)

IgG1 (2)

IgG1,k (5)

IgG2a,k (1)

IgM (3)

Clonality

monoclonal mc (13)

polyclonal pc (49)

Clone

44D7 (1)

IPO-T10 (3)

LG.3A10 (1)

LN-1 (1)

UM7F8 (1)

YUK14 (1)

Format

96-Well Strip Plate (5)

APC (4)

APC Conjugated (5)

Azide-free (2)

Biotin Conjugated (6)

BSA-free (1)

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Cy7 Conjugated (4)

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PE Conjugated (5)

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Epitope

aa213-349 (8)

aa270-406 (8)

aa282-523 (8)

aa285-522 (8)

aa588-615 (7)

aa139-565 (3)

491-540 aa, C-terminal (1)

aa1-50 (1)

aa159-184 (1)

aa360-529 (1)

aa491-540 (1)

aa580-630 (1)

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Publications

No (85)

Yes (2)

Sample Type

Cell Lysates (1)

Plasma (3)

Serum (3)

Tissue Homogenates (2)

Tag

6His, C-terminus (1)

GST (1)

GST, N-terminus (1)

His (4)

His,N-terminus (2)

His-GST (2)

Myc-DDK (Flag) (9)

Species

Human (12)

Mouse (3)

Rat (2)

Source

293T Cells (4)

E. coli (4)

HEK 293 Cells (7)

Human Cells (3)

Wheat Germ Extract (2)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (5)

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IHC-plus™ SLC3A2 / CD98 Heavy Chain Antibody (clone 44D7) LS-B3177

(4.0) Rating

Antibody:

SLC3A2 / CD98 Heavy Chain Mouse anti-Human Monoclonal (44D7) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-Fr, IHC-P, IP

Format:

Unconjugated

Price:

50 µg/$440

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SLC3A2 / CD98 Heavy Chain Antibody (clone LG.3A10) LS-C188834

(4.0) Rating

(1) Publication(s)

Antibody:

SLC3A2 / CD98 Heavy Chain Mouse anti-Human Monoclonal (LG.3A10) Antibody

Reactivity:

Human

Applications:

Flo

Format:

Unconjugated

Price:

100 µg/$626

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SLC3A2 / CD98 Heavy Chain Antibody (clone IPO-T10) LS-C123132

Antibody:

SLC3A2 / CD98 Heavy Chain Mouse anti-Human Monoclonal (IPO-T10) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-Fr

Format:

Unconjugated

Price:

100 µg/$694

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SLC3A2 / CD98 Heavy Chain Antibody (clone UM7F8) LS-C35783

Antibody:

SLC3A2 / CD98 Heavy Chain Mouse anti-Human Monoclonal (UM7F8) Antibody

Reactivity:

Human

Applications:

Flo, Func

Format:

Unconjugated

Price:

100 µg/$626

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SLC3A2 / CD98 Heavy Chain Antibody (aa285-522) LS-C296476

Antibody:

SLC3A2 / CD98 Heavy Chain Rabbit anti-Mouse Polyclonal (aa285-522) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

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SLC3A2 / CD98 Heavy Chain Antibody (aa285-522, HRP) LS-C713002

Antibody:

SLC3A2 / CD98 Heavy Chain Rabbit anti-Mouse Polyclonal (aa285-522) (HRP) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639

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SLC3A2 / CD98 Heavy Chain Antibody (aa285-522, APC) LS-C741319

Antibody:

SLC3A2 / CD98 Heavy Chain Rabbit anti-Mouse Polyclonal (aa285-522) (APC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

• Unconjugated
• HRP
• APC

• Unconjugated
• HRP
• APC

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SLC3A2 / CD98 Heavy Chain Antibody (aa1-50) LS-C290970

Antibody:

SLC3A2 / CD98 Heavy Chain Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

IP

Format:

Unconjugated

Price:

10 µg/$295; 100 µl/$514

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SLC3A2 / CD98 Heavy Chain Antibody (aa360-529) LS-C334231

(4.0) Rating

(1) Publication(s)

Antibody:

SLC3A2 / CD98 Heavy Chain Rabbit anti-Human Polyclonal (aa360-529) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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IHC-plus™ SLC3A2 / CD98 Heavy Chain Antibody (aa89-433) LS-B10246

(4.0) Rating

Antibody:

SLC3A2 / CD98 Heavy Chain Rabbit anti-Human Polyclonal (aa89-433) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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Human SLC3A2 / CD98 Heavy Chain (Sandwich ELISA) ELISA Kit - LS-F10685

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Mouse SLC3A2 / CD98 Heavy Chain (Sandwich ELISA) ELISA Kit - LS-F19022

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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SLC3A2 / CD98 Heavy Chain Antibody (aa139-565) LS-C484786

Antibody:

SLC3A2 / CD98 Heavy Chain Rabbit anti-Mouse Monoclonal (aa139-565) Antibody

Reactivity:

Mouse

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

20 µl/$271; 100 µl/$412

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SLC3A2 / CD98 Heavy Chain Antibody (491-540 aa, C-terminal) LS-C387690

Antibody:

SLC3A2 / CD98 Heavy Chain Rabbit anti-Human Polyclonal (491-540 aa, C-terminal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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SLC3A2 / CD98 Heavy Chain Antibody (aa139-565) LS-C484791

Antibody:

SLC3A2 / CD98 Heavy Chain Rabbit anti-Mouse Polyclonal (aa139-565) Antibody

Reactivity:

Mouse

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$412

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Mouse SLC3A2 / CD98 Heavy Chain Protein (Recombinant His-GST) (aa285-522) - LS-G15458

Source:

E. coli

Tag:

His-GST

Molecular Weight:

53.3 kDa

Price:

10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252

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SLC3A2 / CD98 Heavy Chain Antibody (aa491-540) LS-C743126

Antibody:

SLC3A2 / CD98 Heavy Chain Rabbit anti-Human Polyclonal (aa491-540) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

SLC3A2 / CD98 Heavy Chain Antibody (aa139-565) LS-C484785

Antibody:

SLC3A2 / CD98 Heavy Chain Rabbit anti-Mouse Monoclonal (aa139-565) Antibody

Reactivity:

Mouse

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$412

Select

SLC3A2 / CD98 Heavy Chain Antibody (aa270-406) LS-C373265

Antibody:

SLC3A2 / CD98 Heavy Chain Rabbit anti-Human Polyclonal (aa270-406) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

Select

Human SLC3A2 / CD98 Heavy Chain (Sandwich ELISA) ELISA Kit - LS-F7798

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$730

Select

Human SLC3A2 / CD98 Heavy Chain Protein (Recombinant GST) (Full Length) - LS-G30431

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

84.3 kDa

Price:

10 µg/$479; 25 µg/$670

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Rat SLC3A2 / CD98 Heavy Chain Protein (Recombinant His) (Ala100-Ala527) - LS-G98478

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

49.7 kDa

Price:

100 µg/$843

Select

Mouse SLC3A2 / CD98 Heavy Chain Protein (Recombinant His) (Ala139-Ala565) - LS-G98848

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

49.2 kDa

Price:

50 µg/$721

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SLC3A2 / CD98 Heavy Chain Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118002

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

67.8 kDa

Price:

100 µg/$494

Select

Human SLC3A2 / CD98 Heavy Chain Protein (Recombinant His) (aa213-349) - LS-G15457

Source:

E. coli

Tag:

His

Molecular Weight:

16.8 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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