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Sodium-dependent amino acid transporter. Mediates electrogenic symport of neutral amino acids and sodium ions. Has a broad specificity, with a preference for Ala, followed by His, Cys, Asn, Ser, Gly, Val, Thr, Gln and Met. May mediate sodium-independent transport of cationic amino acids, such as Arg and Lys. Amino acid uptake is pH-dependent, with low transport activities at pH 6.5, intermediate at pH 7.0 and highest between pH 7.5 and 8.5.
Gene Name: | solute carrier family 38, member 4 |
Family/Subfamily: | Transporter , Amino acid transporter |
Synonyms: | SLC38A4, Amino acid transporter A3, ATA3, MNAT3, PAAT, SNAT4, NAT3, MATA3, N amino acid transporter 3 |
Target Sequences: | NM_018018 NP_060488.2 Q969I6 |
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