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SLC35A2 / UGT is a member of the nucleotide-sugar transporter family. The encoded protein is a multi-pass membrane protein. It transports UDP-galactose from the cytosol into Golgi vesicles, where it serves as a glycosyl donor for the generation of glycans. Mutations in this gene cause congenital disorder of glycosylation type IIm (CDG2M). Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Gene Name: | solute carrier family 35 (UDP-galactose transporter), member A2 |
Family/Subfamily: | Transporter , Drug/metabolite transporter |
Synonyms: | SLC35A2, UDP-Gal-Tr, UDP-galactose translocator, UGAT, UGT, UGT2, UGT1, UDP-galactose transporter, UGALT, UGTL |
Target Sequences: | NM_005660 NP_005651.1 P78381 |
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