Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Sodium-dependent and pyrimidine-selective. Exhibits the transport characteristics of the nucleoside transport system cit or N2 subtype (N2/cit) (selective for pyrimidine nucleosides and adenosine). It also transports the antiviral pyrimidine nucleoside analogs 3'-azido-3'-deoxythymidine (AZT) and 2',3'-dideoxycytidine (ddC). It may be involved in the intestinal absorption and renal handling of pyrimidine nucleoside analogs used to treat acquired immunodeficiency syndrome (AIDS). It has the following selective inhibition: adenosine, thymidine, cytidine, uridine >> guanosine, inosine.
Gene Name: | solute carrier family 28 (concentrative nucleoside transporter), member 1 |
Family/Subfamily: | Transporter , Nucleoside:sodium symporter |
Synonyms: | SLC28A1, CNT1, CNT 1, HCNT1 |
Target Sequences: | NM_004213 NP_004204.3 O00337 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.