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SLC28A1

solute carrier family 28 (concentrative nucleoside transporter), member 1

Sodium-dependent and pyrimidine-selective. Exhibits the transport characteristics of the nucleoside transport system cit or N2 subtype (N2/cit) (selective for pyrimidine nucleosides and adenosine). It also transports the antiviral pyrimidine nucleoside analogs 3'-azido-3'-deoxythymidine (AZT) and 2',3'-dideoxycytidine (ddC). It may be involved in the intestinal absorption and renal handling of pyrimidine nucleoside analogs used to treat acquired immunodeficiency syndrome (AIDS). It has the following selective inhibition: adenosine, thymidine, cytidine, uridine >> guanosine, inosine.

Gene Name: solute carrier family 28 (concentrative nucleoside transporter), member 1
Family/Subfamily: Transporter , Nucleoside:sodium symporter
Synonyms: SLC28A1, CNT1, CNT 1, HCNT1
Target Sequences: NM_004213 NP_004204.3 O00337

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Proteins (2)
Over-Expression Lysate (2)
SLC28A1 (2)
No (2)
Myc-DDK (Flag) (2)
Human (1)
293T Cells (1)
HEK 293 Cells (1)
SLC28A1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
71.4 kDa
20 µg/$215
SLC28A1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
71.4 kDa
100 µg/$710
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).