Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. The LFCA import appears to be hormone-regulated in a tissue-specific manner. In adipocytes, but not myocytes, insulin induces a rapid translocation of FATP1 from intracellular compartments to the plasma membrane, paralleled by increased LFCA uptake. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids.
Gene Name: | solute carrier family 27 (fatty acid transporter), member 1 |
Family/Subfamily: | Transporter , Fatty acid transporter |
Synonyms: | SLC27A1, ACSVL5, FATP, FATP1, FATP-1, Fatty acid transport protein 1 |
Target Sequences: | AX015323 CAC07591.1 Q6PCB7 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.