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Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone-3-sulfate (E1S), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA).
Gene Name: | solute carrier family 22 (organic anion transporter), member 8 |
Family/Subfamily: | Transporter , Organic anion transporter |
Synonyms: | SLC22A8, HOAT3, OAT3, ROat3, Roct, Organic anion transporter 3 |
Target Sequences: | NM_004254 NP_004245.2 Q8TCC7 |
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