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Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport, such as absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. May play a role in extracellular matrix and cartilage calcification as well as in vascular calcification. May function as a retroviral receptor as it confers human cells susceptibility to infection to Gibbon Ape Leukemia Virus (GaLV), Simian sarcoma-associated virus (SSAV) and Feline leukemia virus subgroup B (FeLV-B) as well as 10A1 murine leukemia virus (10A1 MLV).
Gene Name: | solute carrier family 20 (phosphate transporter), member 1 |
Family/Subfamily: | Transporter , Phosphate transporter |
Synonyms: | SLC20A1, GLVR1, Pit-1, PIT1, Leukemia virus receptor 1, Phosphate transporter 1, Glvr-1 |
Target Sequences: | NM_005415 NP_005406.3 Q8WUM9 |
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