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SLC18A3 / VACHT

solute carrier family 18 (vesicular acetylcholine transporter), member 3

SLC18A3 / VACHT is a member of the vesicular amine transporter family. The encoded transmembrane protein transports acetylcholine into secretory vesicles for release into the extracellular space. Acetylcholine transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene.

Gene Name: solute carrier family 18 (vesicular acetylcholine transporter), member 3
Family/Subfamily: Transporter , Vesicle amine transporter
Synonyms: SLC18A3, HVAChT, VACHT, RVAChT, Vesicular ACh transporter
Target Sequences: NM_003055 NP_003046.2 Q16572

Publications (2)

1
Retinoic acid worsens ATG10-dependent autophagy impairment in TBK1-mutant hiPSC-derived motoneurons through SQSTM1/p62 accumulation. Alberto Catanese, Florian Olde Heuvel, Medhanie Mulaw, Maria Demestre, Julia Higelin, Gotthold Barbi, Axel Freischmidt, Jochen H Weishaupt, Albert C Ludolph, Francesco Roselli, Tobias M Boeckers. Autophagy. 2019 Oct;15:1719-1737. [Full Text Article] [PubMed:30939964] [PMC:PMC6735587]
2
Peak density of immature nerve cells occurs with high-grade dysplasia in intraductal papillary mucinous neoplasms of the pancreas. Vincent Quoc-Huy Trinh, Joseph Thomas Roland, Jahg Wong, Frank Revetta, Krutika Patel, Chanjuan Shi, Kathleen E DelGiorno, Bruce D Carter, Marcus Chuan Beng Tan. The Journal of pathology. 2022 September;258:69-82. [Full Text Article] [PubMed:35686747] [PMC:PMC9378585] Related Antibodies: LS-B16846.

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
SLC18A3 / VACHT (3)
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GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
SLC18A3 / VACHT Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SLC18A3 / VACHT Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
56.7 kDa
20 µg/$150
SLC18A3 / VACHT Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
56.7 kDa
100 µg/$494
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).