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The mammalian kidney expresses a proton-coupled peptide transporter that is responsible for the absorption of small peptides, as well as beta-lactam antibiotics and other peptide-like drugs, from the tubular filtrate. This transporter, SLC15A2, belongs to the same gene family as SLC15A1 (MIM 600544), the proton-coupled peptide transporter found in the small intestine (Liu et al, 1995 [PubMed 7756356]).
Gene Name: | solute carrier family 15 (oligopeptide transporter), member 2 |
Family/Subfamily: | Transporter , Proton-dependent oligopeptide transporter |
Synonyms: | SLC15A2, HPEPT2, Peptide transporter 2, PEPT2 |
Target Sequences: | NM_021082 NP_066568.3 Q16348 |
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