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SLC14A1 / JK

solute carrier family 14 (urea transporter), member 1 (Kidd blood group)

Urea channel that facilitates transmembrane urea transport down a concentration gradient. A constriction of the transmembrane channel functions as selectivity filter through which urea is expected to pass in dehydrated form. The rate of urea conduction is increased by hypotonic stress. Plays an important role in the kidney medulla collecting ducts, where it allows rapid equilibration between the lumen of the collecting ducts and the interstitium, and thereby prevents water loss driven by the high concentration of urea in the urine. Facilitates urea transport across erythrocyte membranes. May also play a role in transmembrane water transport, possibly by indirect means.

Gene Name: solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
Family/Subfamily: Transporter , Urea transporter
Synonyms: SLC14A1, Kidd Blood Group, HsT1341, HUT11, RACH1, RACH2, SLC14A1 JK, Urea transporter 1, UT-B1, Urea transporter-B1, UT1, UTE, JK, Urea transporter, erythrocyte, UT-B
Target Sequences: NM_015865

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Products
Proteins (10)
Over-Expression Lysate (8)
Recombinant (2)
SLC14A1 / JK (10)
No (10)
GST (1)
Myc-DDK (Flag) (9)
Human (6)
293T Cells (4)
HEK 293 Cells (5)
Wheat Germ Extract (1)
Purified (1)
SLC14A1 / JK Protein - 12.5% SDS-PAGE of human SLC14A1 stained with Coomassie Blue
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Wheat Germ Extract
GST
68.9 kDa
2 µg/$439
SLC14A1 / JK Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
42.3 kDa
100 µg/$494
SLC14A1 / JK Protein - Purified recombinant protein SLC14A1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
42.3 kDa
20 µg/$1,107
SLC14A1 / JK Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
48.2 kDa
100 µg/$494
SLC14A1 / JK Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
48.2 kDa
100 µg/$494
SLC14A1 / JK Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
42.3 kDa
100 µg/$494
SLC14A1 / JK Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
48.2 kDa
20 µg/$150
SLC14A1 / JK Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
42.3 kDa
20 µg/$150
SLC14A1 / JK Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
48.2 kDa
20 µg/$150
SLC14A1 / JK Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
42.3 kDa
20 µg/$150
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).