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SLC10A2 / ASBT

solute carrier family 10 (sodium/bile acid cotransporter), member 2

SLC10A2 / ASBT is a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG).

Gene Name: solute carrier family 10 (sodium/bile acid cotransporter), member 2
Family/Subfamily: Transporter , Bile acid:sodium symporter
Synonyms: SLC10A2, ASBT, ISBT, NTCP2, IBAT, PBAM
Target Sequences: NM_000452 NP_000443.1 Q12908

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Proteins (2)
Over-Expression Lysate (2)
SLC10A2 / ASBT (2)
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Myc-DDK (Flag) (2)
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293T Cells (1)
HEK 293 Cells (1)
SLC10A2 / ASBT Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
37.5 kDa
20 µg/$150
SLC10A2 / ASBT Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
37.5 kDa
100 µg/$494
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).