Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
SLC10A2 / ASBT is a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG).
Gene Name: | solute carrier family 10 (sodium/bile acid cotransporter), member 2 |
Family/Subfamily: | Transporter , Bile acid:sodium symporter |
Synonyms: | SLC10A2, ASBT, ISBT, NTCP2, IBAT, PBAM |
Target Sequences: | NM_000452 NP_000443.1 Q12908 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.