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SLC10A1 / NTCP

solute carrier family 10 (sodium/bile acid cotransporter), member 1

SLC10A1 / NTCP belongs to the sodium/bile acid cotransporter family, which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids; the ileal sodium/bile acid cotransporter with an apical cell localization that absorbs bile acids from the intestinal lumen, bile duct and kidney, and the liver-specific sodium/bile acid cotransporter, represented by this protein, that is found in the basolateral membranes of hepatocytes. Bile acids are the catabolic product of cholesterol metabolism, hence this protein is important for cholesterol homeostasis.

Gene Name: solute carrier family 10 (sodium/bile acid cotransporter), member 1
Family/Subfamily: Transporter , Bile acid:sodium symporter
Synonyms: SLC10A1, Growth-inhibiting protein 29, Na(+)/bile acid cotransporter, Sodium/bile acid cotransporter, Na+/bile acid cotransporter, NTCP, NTCP1
Target Sequences: NM_003049 NP_003040.1 Q14973

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
SLC10A1 / NTCP (3)
No (3)
Myc-DDK (Flag) (3)
Human (2)
293T Cells (1)
HEK 293 Cells (2)
SLC10A1 / NTCP Protein - Purified recombinant protein SLC10A1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
37.9 kDa
20 µg/$1,107
SLC10A1 / NTCP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
37.9 kDa
100 µg/$494
SLC10A1 / NTCP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
37.9 kDa
20 µg/$150
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).