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SLAMF6 / NTBA

SLAM family member 6

SLAMF6 / NTBA is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene Name: SLAM family member 6
Synonyms: SLAMF6, Activating NK receptor, CD352, CD352 antigen, NK-T-B-antigen, NTB-A, NTBA receptor, KALIb, SF2000, SLAM family member 6, Ly108, NTBA, KALI
Target Sequences: IPI00061226.1 Q96DU3

Publications (2)

1
HIV modulates the expression of ligands important in triggering natural killer cell cytotoxic responses on infected primary T-cell blasts. Ward J, Bonaparte M, Sacks J, Guterman J, Fogli M, Mavilio D, Barker E. Blood. 2007 110:1207-14. [PubMed:17513617] [PMC:PMC1939902] Related Antibodies: LS-C40789.
2
Trogocytosis is a gateway to characterize functional diversity in melanoma-specific CD8+ T cell clones. Uzana R, Eisenberg G, Sagi Y, Frankenburg S, Merims S, Amariglio N, Yefenof E, Peretz T, Machlenkin A, Lotem M. Journal of immunology (Baltimore, Md. : 1950). 2012 188:632-40. [PubMed:22156347] Related Antibodies: LS-C40789.

☰ Filters
Products
Proteins (18)
Over-Expression Lysate (6)
Recombinant (12)
SLAMF6 / NTBA (18)
No (18)
6His, C-terminus (1)
AVI-6His, C-terminus (1)
Fc (1)
Fc, C-terminus (2)
GST (1)
His (2)
His,C-terminus (2)
Myc-DDK (Flag) (7)
Human (14)
Mouse (1)
293T Cells (3)
E. coli (1)
HEK 293 Cells (5)
Human (1)
Human Cells (5)
Mammalian Cells (2)
Wheat Germ Extract (1)
Purified (6)
Low endotoxin level (9)
SLAMF6 / NTBA Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
SLAMF6 / NTBA Protein - Purified recombinant protein SLAMF6 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
32.5 kDa
20 µg/$1,107
SLAMF6 / NTBA Protein - 12.5% SDS-PAGE of human SLAMF6 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
56.9 kDa
10 µg/$479; 25 µg/$670
Select
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
50.1 kDa
100 µg/$721
SLAMF6 / NTBA Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
32.5 kDa
100 µg/$494
SLAMF6 / NTBA Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
32.5 kDa
20 µg/$150
SLAMF6 / NTBA Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
25.4 kDa
20 µg/$150
SLAMF6 / NTBA Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
34.2 kDa
20 µg/$150
SLAMF6 / NTBA Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
34.2 kDa
100 µg/$494
SLAMF6 / NTBA Protein - Recombinant Human SLAM Family Member 6/SLAMF6/CD352/NTB-A (C-6His-Avi) Biotinylated
Select
Human
AVI-6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
25.8 kDa
20 µg/$416; 100 µg/$910
SLAMF6 / NTBA Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
25.4 kDa
100 µg/$494
Select
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
24.4 kD
100 µg/$721
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
49.6 kDa
10 µg/$277; 50 µg/$389
Select
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
23.4 kDa
10 µg/$262; 50 µg/$361
Select
Human Cells
None
Less than 1.0 EU/µg protein (determined by LAL method).
23.9 kDa
100 µg/$721
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
24.3 kDa
100 µg/$721
Select
Human Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
49.6kD
10 µg/$277; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
23.98kD
10 µg/$262; 50 µg/$365; 500 µg/$1,585; 1 mg/$2,157
Viewing 1-18 of 18 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).