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Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.
Gene Name: | SIVA1, apoptosis-inducing factor |
Synonyms: | SIVA1, CD27BP, CD27-binding (Siva) protein, Siva-1, SIVA, Siva-2, CD27-binding protein |
Target Sequences: | NM_006427 NP_006418.2 O15304 |
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