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SIRT5 / Sirtuin 5
sirtuin 5
NAD-dependent lysine demalonylase and desuccinylase that specifically removes malonyl and succinyl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro.
| Gene Name: | sirtuin 5 |
| Family/Subfamily: | ADP-Ribosyltransferase , not assigned-ADP-Ribosyltransferase |
| Synonyms: | SIRT5, SIR2L5, Sir2-like 5, SIR2-like protein 5, Sirtuin 5, Sirtuin type 5 |
| Target Sequences: | NM_031244 NP_112534.1 Q9NXA8 |
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Antibodies
(92)
Type
Primary
(92)
Target
SIRT5 / Sirtuin 5
(92)
Reactivity
Human
(76)
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(22)
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(20)
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(3)
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(6)
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(9)
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(3)
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(6)
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(12)
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(32)
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(17)
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(86)
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(70)
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(42)
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(16)
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(2)
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(2)
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(20)
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(72)
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(2)
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(13)
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(3)
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(11)
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(11)
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(6)
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(39)
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(16)
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(8)
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(8)
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(7)
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(7)
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(4)
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(4)
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aa30-46
(1)
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(1)
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(1)
Publications
No
(92)
SIRT5 / Sirtuin 5 Rabbit anti-Human Polyclonal (aa30-46) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$460
SIRT5 / Sirtuin 5 Rabbit anti-Human Polyclonal (aa179-228) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (OTI2F1) Antibody
Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (Carrier-free) (OTI2F1) Antibody
Rat, Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (OTI2A11) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (Carrier-free) (OTI2A11) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
SIRT5 / Sirtuin 5 Rabbit anti-Human Polyclonal (aa184-233) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
SIRT5 / Sirtuin 5 Rabbit anti-Mouse Polyclonal (aa37-310) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
SIRT5 / Sirtuin 5 Rabbit anti-Human Polyclonal (aa37-310) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (OTI1A6) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (Carrier-free) (OTI1A6) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
SIRT5 / Sirtuin 5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (OTI2C4) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (Carrier-free) (OTI2C4) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (OTI1B6) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (Carrier-free) (OTI1B6) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
SIRT5 / Sirtuin 5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IP, WB
Unconjugated
100 µg/$341
SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (OTI 1G9) Antibody
Human
Flo, WB
Unconjugated
100 µl/$434
SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (Carrier-free) (OTI 1G9) Antibody
Human
Flo, WB
Unconjugated, Carrier-free
100 µg/$511
SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (Carrier-free) (OTI 2E12) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (Carrier-free) (OTI 1G5) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
SIRT5 / Sirtuin 5 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$424
SIRT5 / Sirtuin 5 Rabbit anti-Human Polyclonal (aa263-292) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
SIRT5 / Sirtuin 5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
SIRT5 / Sirtuin 5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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product results
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