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SIGLEC7 / CD328

sialic acid binding Ig-like lectin 7

Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).

Gene Name: sialic acid binding Ig-like lectin 7
Family/Subfamily: Immunoglobulin , not assigned-Immunoglobulin
Synonyms: SIGLEC7, AIRM-1, AIRM1, CD328 antigen, CDw328, CD328, D-siglec, QA79, SIGLEC-7, QA79 membrane protein
Target Sequences: NM_014385 NP_055200.1 Q9Y286

☰ Filters
Products
ELISA Kits (5)
Development Kit (1)
Sandwich (4)
SIGLEC7 / CD328 (5)
Human (5)
Product Group
DevKit DuoPlus (1)
96-Well Strip Plate (4)
Antibody Pair and Standard (1)
No (5)
Cell Culture Supernatants (2)
Plasma (5)
Serum (5)
Tissue Homogenates (2)
SIGLEC7 / CD328 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
SIGLEC7 / CD328 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$798
SIGLEC7 / CD328 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
SIGLEC7 / CD328 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$624
SIGLEC7 / CD328 ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
500 Wells/$1,229; 1000 Wells/$1,826
Viewing 1-5 of 5 product results


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Products: ELISA Kits


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).