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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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SIGLEC7 / CD328
sialic acid binding Ig-like lectin 7
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).
| Gene Name: | sialic acid binding Ig-like lectin 7 |
| Family/Subfamily: | Immunoglobulin , not assigned-Immunoglobulin |
| Synonyms: | SIGLEC7, AIRM-1, AIRM1, CD328 antigen, CDw328, CD328, D-siglec, QA79, SIGLEC-7, QA79 membrane protein |
| Target Sequences: | NM_014385 NP_055200.1 Q9Y286 |
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SIGLEC7 / CD328
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SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
SIGLEC7 / CD328 Mouse anti-Human Monoclonal (5-386) Antibody
Human
Flo, IHC, IHC-Fr
Unconjugated
0.1 mg/$385
SIGLEC7 / CD328 Mouse anti-Human Monoclonal (FITC) (5-386) Antibody
Human
Flo, IHC, IHC-Fr
FITC Conjugated
0.1 mg/$432
SIGLEC7 / CD328 Mouse anti-Human Monoclonal (RPE) (5-386) Antibody
Human
Flo
RPE Conjugated
100 Tests/$485
SIGLEC7 / CD328 Mouse anti-Human Monoclonal (Low Endotoxin) (S7.7) Antibody
Human
ELISA, Flo, IP, WB
Unconjugated, Low Endotoxin
0.5 mg/$671
E. coli
His,N-terminus
42.4 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
SIGLEC7 / CD328 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
SIGLEC7 / CD328 Mouse anti-Human Monoclonal (aa18-353) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$408; 500 µl/$608; 1 ml/$758; 2 ml/$996; 5 ml/$1,725
SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa38-121) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$460
SIGLEC7 / CD328 Mouse anti-Human Monoclonal (S7.7) Antibody
Human
ELISA, Flo, IP, WB
Unconjugated
0.1 mg/$385
Sandwich
96-Well Strip Plate
Human
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
SIGLEC7 / CD328 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa407-438) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
SIGLEC7 / CD328 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$351
SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa18-353) Antibody
Human
ICC, IP, WB
Unconjugated
100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182
SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa407-438) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
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