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6737 Mowry Ave
Newark, CA 94560
United States
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SIGLEC11
sialic acid binding Ig-like lectin 11
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,8-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.
| Gene Name: | sialic acid binding Ig-like lectin 11 |
| Synonyms: | SIGLEC11, Sialic acid-binding lectin 11, Siglec-11 |
| Target Sequences: | Q96RL6 Q96RL6 |
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