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Sialylated Lewis a / CA 19-9

Sialylated Lewis Antigen (CA19-9,Carbohydrate antigen, FUT) is a tetrasaccharide that constitutes the sialytated form of Lewis Antigen A. CA19-9 attaches to O-glycans on the plasma membrane where it functions in intercellular recognition. It is a common pancreatic and metastatic colorectal cancer marker because it shows elevated levels alongside CEACAM5 (CEA) expression in late tumors (Vukobrat-Bijedic, 2013; Polat, 2014). CA19-9 is an effective marker for circulating tumor cells, as increased levels of CA19-9 in serum coincide with the quantity of circulating tumor cells from colorectal metastases (Zhao, 2017). Pre- and post treatment levels of CA19-9 are also used as a guage for the efficacy of a given therapy and as a red flag for reoccurrence. In immunohistochemistry, staining of antibodies to CA19-9 is primarily cytoplasmic.

Sialylated Lewis a / CA 19-9 Target Details

Target Name: Sialylated Lewis a / CA 19-9

Publications (2)

1
Potentials and capabilities of the Extracellular Vesicle (EV) Array. Jørgensen MM, Bæk R, Varming K. Journal of Extracellular Vesicles. 2015 4:26048. (IHC; Human) [PubMed:25862471] [PMC:PMC4393420] Related Antibodies: LS-B5680.
2
Profiling of different pancreatic cancer cells used as models for metastatic behaviour shows large variation in their N-glycosylation. Holst S, Belo AI, Giovannetti E, van Die I, Wuhrer M. Scientific reports. 2017 November;7:16623. (Human) [Full Text Article] [PubMed:29192278] [PMC:PMC5709460]

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Antibodies (37)
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Sialylated Lewis a / CA 19-9 (37)
Human (37)
Guinea pig (1)
IHC (10)
IHC-Fr (1)
IHC-P (16)
Flo (5)
ELISA (20)
FLISA (3)
IF (5)
mouse (37)
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PathPlus Cancer (3)
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IgG1 (24)
IgM (8)
IgM,k (5)
monoclonal mc (37)
121SLE (9)
C241:5:1:4 (1)
G1/G1-4 (3)
NS19 (1)
NS19-9 (1)
SPM588 (2)
X91 (1)
APC Conjugated (3)
Azide-free (2)
Biotin Conjugated (3)
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Yes (1)
Sialylated Lewis a / CA 19-9 Antibody - Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
Sialylated Lewis a / CA 19-9 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC-P
Unconjugated
0.25 mg/$545
Sialylated Lewis a / CA 19-9 Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Sialylated Lewis a / CA 19-9 Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-P
Unconjugated
1 mg/$1,104
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Sialylated Lewis a / CA 19-9 Mouse anti-Human Monoclonal (X91) Antibody
Human
IHC
Unconjugated
0.2 mg/$559; 0.5 mg/$752
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Sialylated Lewis a / CA 19-9 Mouse anti-Human Monoclonal (G1/G1-4) Antibody
Human
ELISA
Unconjugated
1 mg/$816
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Sialylated Lewis a / CA 19-9 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA
APC Conjugated
100 µl/$987
Sialylated Lewis a / CA 19-9 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
Sialylated Lewis a / CA 19-9 Mouse anti-Human Monoclonal (Concentrated) (121SLE) Antibody
Human
ELISA, Flo, IHC, IHC-P
Unconjugated, Concentrated
50 µg/$460
Sialylated Lewis a / CA 19-9 Antibody - IHC of paraffin-embedded Human breast tissue using anti-CA19-9 mouse monoclonal antibody.
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Sialylated Lewis a / CA 19-9 Mouse anti-Human Monoclonal (Carrier-free) (NS19-9) Antibody
Human
IF, IHC
Unconjugated, Carrier-free
100 µg/$511
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Sialylated Lewis a / CA 19-9 Mouse anti-Human Monoclonal (C241:5:1:4) Antibody
Human
IHC, IHC-P
Unconjugated
0.1 ml/$275; 0.5 ml/$404; 1 ml/$535
Sialylated Lewis a / CA 19-9 Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
Sialylated Lewis a / CA 19-9 Mouse anti-Human Monoclonal (121SLE) Antibody
Human
IHC-P
Unconjugated
0.05 ml/$460
Sialylated Lewis a / CA 19-9 Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Sialylated Lewis a / CA 19-9 Mouse anti-Human Monoclonal (121SLE) Antibody
Human
IHC-P
Unconjugated
0.1 ml/$314
Sialylated Lewis a / CA 19-9 Antibody - IHC of CA19-9 on FFPE Salivary Gland tissue. This image was taken for the unmodified form of this product. Other forms have not been tested.
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Sialylated Lewis a / CA 19-9 Mouse anti-Human Monoclonal (Ready-to-Use) (121SLE) Antibody
Human
IHC-Fr, IHC-P
Unconjugated, Ready-to-Use
3 ml/$321
Sialylated Lewis a / CA 19-9 Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Sialylated Lewis a / CA 19-9 Mouse anti-Human Monoclonal (121SLE) Antibody
Human
ELISA, IHC-P
Unconjugated
0.05 mg/$460
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Sialylated Lewis a / CA 19-9 Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
1 mg/$1,404
Sialylated Lewis a / CA 19-9 Antibody - Formalin-fixed, paraffin-embedded human gastric carcinoma stained with CA19-9 antibody (121SLE).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Sialylated Lewis a / CA 19-9 Mouse anti-Human Monoclonal (121SLE) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
Sialylated Lewis a / CA 19-9 Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Sialylated Lewis a / CA 19-9 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (121SLE) Antibody
Human
Flo, IF, IHC-P
Unconjugated, Azide-free, BSA-free
50 µg/$460
Sialylated Lewis a / CA 19-9 Antibody - Formalin-fixed, paraffin-embedded human gastric carcinoma stained with CA19-9 antibody (121SLE).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
Sialylated Lewis a / CA 19-9 Mouse anti-Human Monoclonal (Ready-to-Use) (121SLE) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated, Ready-to-Use
7 ml/$574
Sialylated Lewis a / CA 19-9 Antibody - Formalin-fixed, paraffin-embedded human colon carcinoma stained with CA19-9 antibody (SPM588).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Sialylated Lewis a / CA 19-9 Mouse anti-Human Monoclonal (SPM588) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
Sialylated Lewis a / CA 19-9 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Sialylated Lewis a / CA 19-9 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (SPM588) Antibody
Human
IHC-P
Unconjugated, Azide-free, BSA-free
50 µg/$460
Sialylated Lewis a / CA 19-9 Antibody - IHC of paraffin-embedded Human breast tissue using anti-CA19-9 mouse monoclonal antibody.
Select
Sialylated Lewis a / CA 19-9 Mouse anti-Human Monoclonal (NS19) Antibody
Human
IHC, IHC-P
Unconjugated
100 µl/$434
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Sialylated Lewis a / CA 19-9 Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-P
Unconjugated
500 µl/$1,054
Sialylated Lewis a / CA 19-9 Antibody - CA19-9 Antibody in Immunohistochemistry (IHC)
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Sialylated Lewis a / CA 19-9 Mouse anti-Human Monoclonal (121SLE) Antibody
Guinea pig, Human
ELISA, IHC-P
Unconjugated
100 µg/$372
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Sialylated Lewis a / CA 19-9 Mouse anti-Human Monoclonal (G1/G1-4) Antibody
Human
ELISA
Unconjugated
1 mg/$816
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Sialylated Lewis a / CA 19-9 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
100 µl/$987
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Sialylated Lewis a / CA 19-9 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA
APC Conjugated
100 µl/$987
Select
Sialylated Lewis a / CA 19-9 Mouse anti-Human Monoclonal (G1/G1-4) Antibody
Human
ELISA
Unconjugated
1 mg/$816
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).