SHSF1 / SHFM1

26S proteasome complex subunit SEM1

Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis (PubMed:15117943). Component <br>of the TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and <br>either centrin CETN2 or CETN3 (PubMed:22307388). The TREX-2 complex functions in docking export-competent <br>ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 <br>participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear <br>periphery. Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and thus <br>transcription-associated genomic instability. R-loop accumulation increases in DSS1-depleted cells.

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Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

SHSF1 / SHFM1 (4)

Publications

No (4)

Tag

GST (1)

His (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (2)

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Human SHSF1 / SHFM1 Protein (Recombinant His) - LS-G2660

Source:

E. coli

Tag:

His

Price:

50 µg/$411; 250 µg/$985; 10 µg/$276

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Human SHSF1 / SHFM1 Protein (Recombinant GST) (Full Length) - LS-G31044

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

34.7 kDa

Price:

10 µg/$479; 25 µg/$670

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Human SHSF1 / SHFM1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75466

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

8.1 kDa

Price:

20 µg/$150

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SHSF1 / SHFM1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115409

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

8.1 kDa

Price:

100 µg/$494

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