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Controls cell shape changes in the neuroepithelium during neural tube closure. Induces apical constriction in epithelial cells by promoting the apical accumulation of F-actin and myosin II, and probably by bundling stress fibers. Induces apicobasal cell elongation by redistributing gamma-tubulin and directing the assembly of robust apicobasal microtubule arrays.
Gene Name: | Shroom Family Member 3 |
Synonyms: | SHROOM3, APXL3, F-actin-binding protein, HShrmL, Protein Shroom3, SHRM, MSTP013, ShrmL, KIAA1481, Shroom family member 3, Shroom-related protein |
Target Sequences: | NP_065910.3 Q8TF72 |
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