SHOX2

short stature homeobox 2

SHOX2 is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients. SHOX2 (also called SHOT for SHOX homologous gene on chromosome 3) has two alternatively spliced transcript variants, SHOX2a and SHOX2b, that have identical homeodomains and share a C-terminal 14-amino acid residue motif characteristic for craniofacially expressed homeodomain proteins. The differences between SHOX2a and SHOX2b reside within the N-termini and an alternatively spliced exon in the C termini. SHOX2 maps to 3q25-q26.1 and is considered to be a candidate gene for Cornelia de Lange syndrome.

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Products

Proteins (8)

Type

Over-Expression Lysate (4)

Recombinant (4)

Target

SHOX2 (8)

Publications

No (8)

Tag

GST (1)

GST, N-terminus (1)

His, N-Terminal (1)

Myc-DDK (Flag) (5)

Species

Human (6)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (3)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human SHOX2 Protein (Recombinant GST, N-terminus) (aa117-204) - LS-G60087

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human SHOX2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67630

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.4 kDa

Price:

20 µg/$1,107

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Human SHOX2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80315

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.4 kDa

Price:

20 µg/$150

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Human SHOX2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80316

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.8 kDa

Price:

20 µg/$150

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SHOX2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115027

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.8 kDa

Price:

100 µg/$494

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SHOX2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G128038

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.4 kDa

Price:

100 µg/$494

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Human SHOX2 Protein (Recombinant His, N-Terminal) - LS-G144202

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

34.8 kDa

Price:

50 µg/$419

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Human SHOX2 Protein (Recombinant GST) (Full Length) - LS-G30410

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

64 kDa

Price:

10 µg/$479; 25 µg/$670

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