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Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.
Gene Name: | soc-2 suppressor of clear homolog (C. elegans) |
Synonyms: | SHOC2, KIAA0862, Protein sur-8 homolog, Protein soc-2 homolog, SOC-2, SOC2, SUR-8, SUR8, SIAA0862 |
Target Sequences: | NM_007373 NP_031399.2 Q9UQ13 |
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