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SHANK1
SH3 and multiple ankyrin repeat domains 1
Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction.
| Gene Name: | SH3 and multiple ankyrin repeat domains 1 |
| Synonyms: | SHANK1, SPANK-1, SSTR-interacting protein, Synamon, SSTRIP |
| Target Sequences: | NM_016148 NP_057232.2 Q9Y566 |
Publications (1)
1
Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2. Schmeisser MJ, Ey E, Wegener S, Bockmann J, Stempel AV, Kuebler A, Janssen AL, Udvardi PT, Shiban E, Spilker C, Balschun D, Skryabin BV, Dieck St, Smalla KH, Montag D, Leblond CS, Faure P, Torquet N, Le Sourd AM, Toro R, Grabrucker AM, Shoichet SA, Schmit. Nature. 2012 486:256-60. (WB; Mouse)
[PubMed:22699619]
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Antibodies
(13)
Type
Primary
(13)
Target
SHANK1
(13)
Reactivity
Human
(13)
Mouse
(10)
Rat
(12)
Application
IHC
(12)
WB
(13)
ELISA
(1)
ICC
(10)
IF
(9)
IP
(10)
Host
rabbit
(1)
mouse
(12)
Isotype
IgG
(1)
IgG1
(12)
Clonality
monoclonal mc
(12)
polyclonal pc
(1)
Clone
S22-21
(10)
Format
APC Conjugated
(1)
Atto 390 Conjugated
(1)
Atto 488 Conjugated
(1)
Atto 594 Conjugated
(1)
Biotin Conjugated
(1)
FITC Conjugated
(1)
PerCP Conjugated
(1)
RPE Conjugated
(1)
Unconjugated
(5)
Epitope
aa469-691
(11)
aa84-309
(1)
Publications
No
(13)
SHANK1 Mouse anti-Human Monoclonal (aa469-691) (S22-21) Antibody
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
100 µg/$537
SHANK1 Mouse anti-Rat Monoclonal (aa469-691) (S22-21) Antibody
Mouse, Rat, Human
ICC, IHC, IP, WB
Unconjugated
100 µg/$442
SHANK1 Mouse anti-Rat Monoclonal (aa469-691) (Biotin) (S22-21) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
Biotin Conjugated
100 µg/$475
SHANK1 Mouse anti-Rat Monoclonal (aa469-691) (FITC) (S22-21) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
FITC Conjugated
100 µg/$472
SHANK1 Mouse anti-Rat Monoclonal (aa469-691) (Atto 488) (S22-21) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
Atto 488 Conjugated
100 µg/$479
SHANK1 Mouse anti-Rat Monoclonal (aa469-691) (Atto 390) (S22-21) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
Atto 390 Conjugated
100 µg/$479
SHANK1 Mouse anti-Rat Monoclonal (aa469-691) (Atto 594) (S22-21) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
Atto 594 Conjugated
100 µg/$479
SHANK1 Mouse anti-Rat Monoclonal (aa469-691) (PerCP) (S22-21) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
PerCP Conjugated
100 µg/$478
SHANK1 Mouse anti-Rat Monoclonal (aa469-691) (APC) (S22-21) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
APC Conjugated
100 µg/$478
SHANK1 Mouse anti-Rat Monoclonal (aa469-691) (RPE) (S22-21) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
RPE Conjugated
100 µg/$477
SHANK1 Mouse anti-Rat Monoclonal (aa84-309) Antibody
Rat, Human
IHC, IP, WB
Unconjugated
100 µg/$665
SHANK1 Mouse anti-Rat Monoclonal (aa469-691) Antibody
Rat, Human
IHC, WB
Unconjugated
100 µg/$665
SHANK1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
Viewing 1-13
of 13
product results
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